Thiamine deficiency neuropathy

Abstract

Despite the fact that thiamine deficiency neuropathy is increasing in incidence in our society, it remains an underdiagnosed disorder. The typical complaints of weakness and burning feet are often regarded as trivial by the attending physician. Electrophysiologic studies are sensitive and often provide supportive evidence to aid in the diagnosis. Since chronic pain therapy is often ineffective, a high index of suspicion should be maintained to help ensure early diagnosis and successful intervention.

Parkinson’s Disease and Peripheral Neuropathy

“…The most common causes of peripheral neuropathy are metabolic or endocrine disorders such as with diabetes mellitus, uremia, or thyroid disease, infections such as with human immunodeficiency virus or leprosy, toxic effects as with chemotherapy or alcohol excess, genetic disorders such as with Charcot-Marie-Tooth disease, amongst other causes. Another potentially underdiagnosed cause of peripheral neuropathy is a nutritional deficiency such as with insufficient vitamin B1, vitamin B6, vitamin B12, folate or thiamine [13,14]. Many other causes of peripheral neuropathy occur, but between 40-50% of patients with peripheral neuropathy have no determined cause for their peripheral neuropathy, leading to its designation as an idiopathic peripheral neuropathy [15].…”

A Discussion on Teacher Effectiveness in Curriculum in Kenya with Focus on Makadara Division

“…These issues need to be addressed if we are to become a developed nation because the children are the future leaders. According to Skelton C. (1989) some communities and religious groups encourage girls to sit away from boys. Children are aware of such cultural requirements from very early on.…”