Thiamine and sudden death in sleep of South-East Asian refugees

Munger, RonaldG.; Booton, ElizabethA.

doi:10.1016/0140-6736(90)91154-3

Cited by 16 publications

(5 citation statements)

References 4 publications

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“…Thiamine deficiency is considered a possible cause of such sudden deaths. 5 No laboratory diagnosis was made in this study because there was no such facility in the hospital and a tube of blood would need to be drawn and protected from light before the administration of thiamine, which was not done. To save these patients was the priority.…”

Section: Cardiac Beriberimentioning

confidence: 99%

Cardiac Beriberi among Illegal Mainland Chinese Immigrants

et al. 2001

J Int Med Res

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The most common symptoms of chronic beriberi due to thiamine deficiency include dyspnoea, fatigue, leg oedema, lower extremity weakness and numbness. When collapsed peripheral circulation, metabolic acidosis, or shock are present, the disease has advanced from chronic beriberi to pernicious or fulminating beriberi heart failure (Shoshin beriberi). We report two patients with fulminating beriberi; both of whom had been incarcerated at a detention centre for 5 months before hospitalization. A prolonged monotonous diet, low in thiamine, was a major risk factor in both patients. Thiamine deficiency should be considered for any patient with symptoms and signs compatible with beriberi.

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Section: Cardiac Beriberimentioning

confidence: 99%

Cardiac Beriberi among Illegal Mainland Chinese Immigrants

et al. 2001

J Int Med Res

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“…Low levels of potassium [10] and vitamin B deficiencies have been suggested to play a role in these deaths [11]. Studies on the diet of Laotian refugees among whom similar deaths occur did not substantiate the hypothesis, and the results could not account for the predominance of males among the victims as both men and women shared the same diet.…”

Section: Hypotheses Proposed To Explain Sundmentioning

confidence: 89%

Sudden unexpected nocturnal deaths among Thai immigrant workers in Singapore

et al. 1994

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Sudden Unexpected Nocturnal Deaths (SUND) occur in young, apparently healthy immigrant workers from Thailand, the Philippines and Bangladesh living among ex-patriot labour forces in countries such as Singapore and Saudi Arabia. Several factors associated with these deaths are similar to those observed for Sudden Infant Death Syndrome (SIDS): sleep related and mainly nocturnal occurrence; no prodromal illnesses other than mild respiratory tract infection; exposure to cigarette smoke; absence of invasive microorganisms at autopsy. The hypotheses proposed to explain these deaths in adults are examined. Based on our studies of the role toxigenic bacteria might play in some cases of SIDS, we suggest a new approach to the investigation of SUND.

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“… 9 Several hypotheses about the cause of death had been proposed: hypokalemia, thiamine deficiency, noxious agents, and emotional stress. 7 , 8 , 9 , 10 None of these hypotheses have been proven. However, ventricular fibrillation (VF) was implicated the rhythm at the terminal event or was the resuscitated rhythm in survivors of SUDS.…”

Section: Identification Of Brugada Marker In Sudden Unexplained Death...mentioning

confidence: 99%