Thermoset-Thermoplastic Nanostructured Blends

Fourquet_Bandeira, Cirlene; Montoro, Sérgio Roberto; Brocks, Thatiane

doi:10.1016/b978-0-323-39408-6.00001-7

Design and Applications of Nanostructured Polymer Blends and Nanocomposite Systems 2016

DOI: 10.1016/b978-0-323-39408-6.00001-7

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Thermoset-Thermoplastic Nanostructured Blends

Cirlene Fourquet_Bandeira

Sérgio Roberto Montoro

Thatiane Brocks

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Cited by 2 publications

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Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes

Büyüköz

Sharma

et al. 2017

Acta Biomaterialia

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This manuscript focuses on the effect of microstructure and mechanical properties of gelatin-based 3D conduits on the transdifferentiation of mesenchymal stem cells to Schwann cell-like phenotypes. This work builds on our recently accepted manuscript in Acta Biomaterialia focused on multifunctional 2D films, and focuses on 3D microstructured conduits designed to overcome limitations of current strategies to facilitate peripheral nerve regeneration. The comparison between conduits fabricated with nanofibrous, macroporous and ladder-like microstructures showed that the ladder-like conduits showed the most favorable environment for MSC transdifferentiation to Schwann-cell like phenotypes, as seen by both immunolabeling as well as secretion of neurotrophic factors. This work demonstrates the importance of controlling the 3D microstructure to facilitate tissue engineering strategies involving stem cells that can serve as promising approaches for peripheral nerve regeneration.

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Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes

Büyüköz

Sharma

et al. 2017

Acta Biomaterialia

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Compression and fracture behavior of leather particulate reinforced polymer composites

Surana¹,

Bedi

Bhinder

et al. 2020

Mater. Res. Express

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Strategies are suggested for the waste utilization of industrial leather by preparing composites with epoxy and high-density polyethylene (HDPE). The addition of leather improves the average specific compression toughness of epoxy by 29%. The fracture surface analysis suggests the incorporation of leather microparticles leads to a transition of failure mode of epoxy from brittle to ductile. In addition, the dynamic strength of the leather/epoxy composite is found to be 69% higher than that of neat epoxy. However, no significant changes are observed when HDPE is infiltrated with leather. Apart from dispersing the leather particles directly in polymer, a novel strategy is presented here in which leather/HDPE microfibers are prepared and then used to reinforce the epoxy matrix. The specific compression modulus of this composite blend is 8% and 65% higher than epoxy and HDPE, respectively. Fractography is further carried out on the failed specimens to understand the failure mechanism in each composite. A change in the failure mode is observed when epoxy is reinforced either with leather particles or the microfiber. While the failure strength of the microfiber is found to be higher than epoxy, the strength of microfiber/epoxy interface is lower than that of epoxy.

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Thermoset-Thermoplastic Nanostructured Blends

Cited by 2 publications

References 24 publications

Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes

Gelatin-based 3D conduits for transdifferentiation of mesenchymal stem cells into Schwann cell-like phenotypes

Compression and fracture behavior of leather particulate reinforced polymer composites

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