Thermoresponsive Cellulose Nanocrystals Protecting Macrophage Cells From Oxidative Stress
José Pinheiro,
Nívia Marques,
Maylla Silva
et al.
Abstract:Cellulose nanocrystals (CNCs) were grafted with poly(N-isopropylacrylamide) (PNIPAM) chains, by means of the grafting from route, using the TEMED/KPS redox pair as free-radical initiators. The confirmation of grafting was revealed by 13C NMR spectra. In a test with murine macrophages (RAW 264.7 cell line), CNC-g-PNIPAM copolymers did not affect cell viability nor RAW cell oxide nitric production. Raw cells exposed to oxidative stress induced by H2O2 decreased the cell viability (~ 60%) and increased lipid pero… Show more
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