Thermogravimetric analysis and chemometric based methods for soil examination: Application to soil forensics

Chauhan, Rohini; Kumar, Raj; Diwan, P.K.; Sharma, Vishal

doi:10.1016/j.forc.2019.100191

Cited by 37 publications

(15 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thermogravimetric techniques have been largely applied to complex matrix as analytical tool that does not require sample pretreatment nor clean-up (Toth et al, 2010;Fonseca et al, 2012;Materazzi et al, 2015Materazzi et al, , 2017aPapadopoulos et al, 2016;Risoluti et al, 2016bRisoluti et al, , 2017Bach and Chen, 2017;Catauro et al, 2018) and permits to rapidly obtain both qualitative and quantitative outcomes (Skreiberg et al, 2011;Materazzi et al, 2014a,b;Napoli et al, 2014;Shan-Yang et al, 2015;Marcilla et al, 2017). Recently, a novel approach based on the association of thermogravimetric analysis (TGA) and chemometrics has been proposed in different fields (Pappa et al, 2003;Khanmohammadi et al, 2012;Caramés-Alfaya et al, 2013;Chauhan et al, 2020), including the investigation of biological samples for clinical analysis (Risoluti et al, 2016a(Risoluti et al, , 2018aMaterazzi et al, 2017a). Themogravimetry, in fact, with respect to clinical specimens, presents the advantage of processing samples without requiring any sample manipulation and the resulting curves reflect the characteristic composition of the sample in few microliters of sample.…”

Section: Introductionmentioning

confidence: 99%

An Innovative Multilevel Test for Hemoglobinopathies: TGA/Chemometrics Simultaneously Identifies and Classifies Sickle Cell Disease From Thalassemia

Risoluti

Caprari

Gullifa

et al. 2020

Front. Mol. Biosci.

View full text Add to dashboard Cite

Introduction: Hemoglobinopathies are the most common genetic disorder wordlwide and because of migrations are become an emerging global health problem. Screening programmes for Sickle cell disease and Thalassemia have been implemented in some countries, but are not a common practice, due to a lack in the accuracy of the methods and to the costs of the analyses. Objectives: The objective of this study was the application of the thermogravimetry coupled to chemometrics as new screening method to perform an early diagnosis of thalassemia and sickle cell disease. Methods: Whole blood samples (30 µL) from sickle cell anemia and thalassemia patients were analyzed using the thermobalance TG7 and the resulting curves were compared with those of healthy individuals. A chemometric approach based on Principal Components Analysis (PCA) was exploited to enhance correlation between thermogravimetric profiles and a model of prediction by Partial Least Square Discriminant Analysis (PLS-DA) was developed and validated. Results: The characteristic profile of the blood sample thermal decomposition and the first derivative of the TG curve showed that patients were clearly distinguished from healthy individuals as a result of different amounts of water and corpuscular fraction of blood. The chemometric approach based on PCA allowed a quick identification of differences between healthy subjects and patients and also between thalassemic and sickle cell anemia subjects. Chemometric tools (PLS-DA) were used to validate a model of prediction to process the thermogravimetric curves and to obtain in 1 h an accurate diagnosis. The TGA/Chemometric test permitted to perform first level test for hemoglobinopathies with the same accuracy of confirmatory analyses obtained by the molecular investigation. Conclusions: A screening test based on the coupling of thermogravimetry and chemometrics was optimized for the differential diagnosis of hemoglobinopathies. The novel test is able to simultaneously perform a simple and fast diagnosis of sickle cell Risoluti et al. Innovative Multilevel Test for Hemoglobinopathies anemia or thalassemia, in a single analysis of few microliters of non-pretreated whole blood at low cost, and with high accuracy. Moreover this method results particularly suitable in pediatric patients as it requires small sample volumes and is able to characterize also transfused patients.

show abstract

Section: Introductionmentioning

confidence: 99%

An Innovative Multilevel Test for Hemoglobinopathies: TGA/Chemometrics Simultaneously Identifies and Classifies Sickle Cell Disease From Thalassemia

Risoluti

Caprari

Gullifa

et al. 2020

Front. Mol. Biosci.

View full text Add to dashboard Cite

show abstract

“…This tool has already found its application in forensic science 20–30 in analysis of fire debris 21 and in bloodstain investigations 22 . In addition to this, for examination of soil samples, chemometrics has been applied for analysis of UV‐Vis spectra, 24 mass spectra, 25 for analysis of data collected using X‐ray fluorescence and scattering spectrometry, 26 as well as thermogravimetric analysis 27 . The details about advantages of chemometrics 23 and its use coupled with different instrumental methods for forensic purposes are described in review articles 18,22,23 …”

Section: Introductionmentioning

confidence: 99%

“…18 Chemometrics is the area of chemistry devised to elicit all kinds of useful information from multidimensional data. 19 This tool has already found its application in forensic science [20][21][22][23][24][25][26][27][28][29][30] in analysis of fire debris 21 and in bloodstain investigations. 22 In addition to this, for examination of soil samples, chemometrics has been applied for analysis of UV-Vis spectra, 24 mass spectra, 25 for analysis of data collected using X-ray fluorescence and scattering spectrometry, 26 as well as thermogravimetric analysis.…”

Section: Introductionmentioning

confidence: 99%

“…22 In addition to this, for examination of soil samples, chemometrics has been applied for analysis of UV-Vis spectra, 24 mass spectra, 25 for analysis of data collected using X-ray fluorescence and scattering spectrometry, 26 as well as thermogravimetric analysis. 27 The details about advantages of chemometrics 23 and its use coupled with different instrumental methods for forensic purposes are described in review articles. 18,22,23 For this study, it is most important to state that IR spectroscopy coupled with attenuate total reflection accessory has been used in trace evidence analysis.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Classification of urban soils for forensic purposes using supervised self‐organizing maps

Idrizi

Najdoski

Kuzmanovski

2021

Journal of Chemometrics

View full text Add to dashboard Cite

Due to its transferability, soil has been commonly used as evidence in criminal investigations. In this work, urban soil samples taken from five parks are subject of analysis. Infrared spectroscopy was used as experimental technique. Using this technique, a total number of 80 samples of urban soils were examined. The infrared spectra were properly pre‐processed and were further used for development of classification models based on supervised self‐organizing maps. In order to perform the variable selection and the optimization of the supervised self‐organizing maps in automated manner, genetic algorithms were employed. Using this approach, for three locations with our models, we are able to successfully predict all samples used for external validation, while for the remaining two locations, 96% of the samples, used for external validation, were successfully classified by the developed models. In addition to this, the developed models were used for examination of influence of the weather and the seasonal changes on the composition of the soil. For this purpose, 3 years after the initial soil samples were collected, additional 12 samples were analyzed. All these samples were correctly classified by the previously developed model.

show abstract

“…Recently, the thermogravimetry associated with chemometric analysis has been proposed as a novel technique that is able to analyze complex matrices [ 13 , 14 , 15 , 16 ] because it permits qualitative and quantitative analysis [ 17 , 18 , 19 , 20 , 21 , 22 ] without any pretreatment. In addition, this approach provided promising results for the estimation of a PMI in the vitreous humor [ 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Application of Innovative TGA/Chemometric Approach for Forensic Purposes: The Estimation of the Time since Death in Contaminated Specimens

et al. 2021

View full text Add to dashboard Cite

Chronothanatology has always been a challenge in forensic sciences. Therefore, the importance of a multidisciplinary approach for the characterization of matrices (organs, tissues, or fluids) that respond linearly to the postmortem interval (PMI) is emerging increasingly. The vitreous humor is particularly suitable for studies aimed at assessing time-related modifications because it is topographically isolated and well-protected. In this work, a novel approach based on thermogravimetry and chemometrics was used to estimate the time since death in the vitreous humor and to collect a databank of samples derived from postmortem examinations after medico–legal evaluation. In this study, contaminated and uncontaminated specimens with tissue fragments were included in order to develop a classification model to predict time of death based on partial least squares discriminant analysis (PLS-DA) that was as robust as possible. Results demonstrate the possibility to correctly predict the PMI even in contaminated samples, with an accuracy not lower than 70%. In addition, the correlation coefficient of the measured versus predicted outcomes was found to be 0.9978, confirming the ability of the model to extend its feasibility even to such situations involving contaminated vitreous humor.

show abstract

Thermogravimetric analysis and chemometric based methods for soil examination: Application to soil forensics

Cited by 37 publications

References 49 publications

An Innovative Multilevel Test for Hemoglobinopathies: TGA/Chemometrics Simultaneously Identifies and Classifies Sickle Cell Disease From Thalassemia

An Innovative Multilevel Test for Hemoglobinopathies: TGA/Chemometrics Simultaneously Identifies and Classifies Sickle Cell Disease From Thalassemia

Classification of urban soils for forensic purposes using supervised self‐organizing maps

Application of Innovative TGA/Chemometric Approach for Forensic Purposes: The Estimation of the Time since Death in Contaminated Specimens

Contact Info

Product

Resources

About