Thermogram of idiopathic segmental anhidrosis

Abstract

Abstract-Objective:To assess the frequency of hematologic malignancies at diagnosis and to determine the incidence and predictors of malignant transformation during follow-up in patients with polyneuropathy associated with monoclonal gammopathy. Methods: Potential predictors of malignant transformation from medical history, hematologic, neurologic, and laboratory examination performed each 6 months were evaluated by univariable and multivariable Cox proportional hazard analysis. Results: Of 193 patients with polyneuropathy associated with monoclonal gammopathy, 17 patients had a hematologic malignancy at diagnosis. The incidence rate of malignant transformation in 176 patients without a malignancy at diagnosis was 2.7/100 patient years. Weight loss, progression of the polyneuropathy, unexplained fever or night sweats, and M-protein level were independent predictors. Conclusions: Since hematologic malignancies occur frequently in polyneuropathy associated with monoclonal gammopathy, the authors suggest that all patients should be screened at diagnosis and subsequently during follow-up if malignant transformation is suspected.

Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan

“…Acquired idiopathic generalized anhidrosis is a type of idiopathic anhidrosis. It affects nearly the entire body, and can be differentiated from anhidrosis with segmental spinal or segmental distribution of anhidrotic areas, such as idiopathic segmental anhidrosis and Ross syndrome (Fig. ).…”

Idiopathic segmental anhidrosis associated with varicella

“…Dear Editor, Idiopathic anhidrosis is classified into two categories, acquired idiopathic generalized anhidrosis and segmental anhidrosis, and the latter includes Ross syndrome, Harlequin syndrome and idiopathic segmental anhidrosis (ISA). 1 Differing from these syndromes, ISA has no other obvious neurological symptoms. Although the causes of ISA remain unclear, several cases of segmental anhidrosis following herpes zoster have been Correspondence: Kazuo Kurihara, M.D., Division of Dermatology, Fuji City General Hospital, 50 Takashimatyou, Fuji, Shizuoka 417-8567, Japan.…”