Thermodynamics of the formation of complexes of copper(II) ions and glycylglycine in aqueous solutions at 298 K according to calorimetry data

Kochergina, L. A.; Emel’yanov, A. V.

doi:10.1134/s0036024415040135

Cited by 8 publications

(3 citation statements)

References 31 publications

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“…An example is the cis to trans isomer conversion of N-phosphoryl thioureas, where similar −ΔH = (13-15) kJ mol −1 values were obtained. 103 The negative value in our system reveals that the conversion of the {NH 2 ,N − ,COO − } peptide-type copper(II) complex to its {NH 2 ,N im } histamine-type linkage isomer is an exothermic process. This can be explained by the fact that the protonation of the backbone amide group is favoured at pH ∼ 5, taken that its basicity is much higher compared to the imidazole sidechain nitrogen.…”

Section: Microcalorimetric Experimentsmentioning

confidence: 78%

“…Accordingly, the formation of peptide-type coordination mode in the reaction of Gly-Gly with copper(II) was shown to be slightly endothermic (1.6-2.8 kJ mol −1 ). 103 In addition, the positive mesomeric effect of the imidazole ring increases the electron density on the nitrogen donor group, strengthening the copper(II)-N im bond, as demonstrated by the negative standard reaction enthalpy related to the formation of the copper(II)-histamine [CuL] 2+ complex (−54.3 kJ mol −1 ). 104…”

Section: Microcalorimetric Experimentsmentioning

confidence: 99%

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Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(ii)–dipeptide systems

et al. 2017

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The investigation of the linkage isomers of biologically essential and kinetically labile metal complexes in aqueous solutions poses a challenge, as these microspecies cannot be separately studied. Therefore, derivatives are commonly used to initially determine the stability or spectral characteristics of at least one of the isomers. Here we directly detect the isomers, describe the metal ion coordination sphere, speciation and thermodynamic parameters by a synergistic application of temperature dependent EPR and CD spectroscopic measurements in copper(ii)-dipeptide systems including His-Gly and His-Ala ligands. The ΔH = (-23 ± 4) kJ mol value of the standard enthalpy change corresponding to the peptide-type to histamine-type isomerisation equilibrium of the [CuL] complex was corroborated by several techniques. The preferential coordination of the side-chains was observed at lower temperatures, whereas, metal-binding of the backbone atoms became favourable upon increasing temperature. This study exemplifies the necessity of using temperature dependent multiple methodologies for a reliable description of similar systems for upstream applications.

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Section: Microcalorimetric Experimentsmentioning

confidence: 78%

Section: Microcalorimetric Experimentsmentioning

confidence: 99%

Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(ii)–dipeptide systems

et al. 2017

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“…Координационные соединения катионов металлов находят широкое применение в качестве маркеров для исследования различных биохимических процессов, хорошо изучены различные металлокомплексные соединения, способные к образованию наночастиц [2,3]. Другой важной задачей является изучение физикохимических свойств металлокомплексов, оказывать влияние на биологические процессы [4].…”

Section: Introductionunclassified

Synthesis and Physicochemical Study of the Cerium and Cefazolin Metal Complex

Крюков¹,

Feofanova²,

Скобин³

et al. 2021

Physical and Chemical Aspects of the Study of Clusters, Nanostructures and Nanomaterials

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В данной работе коллективом авторов путём взаимодействия водных растворов хлорида трёхвалентного церия и натриевой соли цефазолина получено и выделено в твердом виде металлокомплексное соединение. Его элементный состав установлен с помощью метода рентгеноспектрального электронно-зондового анализа, описаны термические характеристики данного соединения, температура его разложения, состав и способ координации внутренней сферы данного металлокомплекса был уточнен методами термогравиметрии, и дифференциальной сканирующей калориметрии и методом ИК-спектроскопии. На основании полученных данных установлено, что внутренняя сфера металллокомплекса содержит в своем составе три молекулы цефазолина и три молекулы внутрисферной воды. Состав внутренней сферы отвечает брутто-формуле [CeCzl(HO) ]. На основании данных ИК- спектроскопии сделаны выводы о координации цефазолина к центральному иону через амидную и карбоксильную группы. In this work, a team of authors obtained and isolated in solid form a metal complex compound by the interaction of aqueous solutions of trivalent cerium chloride and sodium salt of cefazolin. Its elemental composition was determined using the X-ray spectral electron probe analysis. The thermal characteristics of this compound, the temperature of its decomposition, the composition and the method of coordination of the inner sphere of this metal complex were clarified by the methods of thermogravimetry, differential scanning calorimetry and IR spectroscopy. Based on the data obtained, the inner sphere of the metal complex contains three molecules of cefazolin and three molecules of inner-sphere water. The composition of the inner sphere corresponds to the formula [CeCzl(HO) ]. Taking into account IR spectroscopy data, the authors concluded that the most likely way of coordination of cefazolin to the central ion is through the amide and carboxyl groups.

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Constants of the Stability of Glycylglycinate Complexes of Copper(II) in Water–Ethanol Solutions

Исаева

Молчанов

Kipyatkov

et al. 2019

Russ. J. Phys. Chem.

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Thermodynamics of the formation of complexes of copper(II) ions and glycylglycine in aqueous solutions at 298 K according to calorimetry data

Cited by 8 publications

References 31 publications

Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(ii)–dipeptide systems

Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(ii)–dipeptide systems

Synthesis and Physicochemical Study of the Cerium and Cefazolin Metal Complex

Constants of the Stability of Glycylglycinate Complexes of Copper(II) in Water–Ethanol Solutions

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