Abstract:Heat
capacities of the antiviral and antiparkinsonian drug amantadine
hydrochloride in the crystalline state were measured by adiabatic
and differential scanning calorimetry in the temperature range from
5 K to 470 K. Two unresolved low-enthalpy solid-to-solid phase transitions
with peak maxima at 120.0 K and 123.1 K were detected. Thermodynamic
functions for crystalline amantadine hydrochloride were derived from
the data obtained. Decomposition of amantadine hydrochloride was studied
by the Knudsen effusion m… Show more
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