Thermodynamically stable vesicle formation of biodegradable double mPEG-tailed amphiphiles with sulfonate head group

Ghosh, R.; Dey, Joykrishna; Kumar, B. V. N. Phani

doi:10.1039/d0ra05613h

Cited by 3 publications

(3 citation statements)

References 55 publications

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“…The proportion of electrostatic interaction energy in the Tween 20 system is 68.1% greater than that in the C 12 (EO) 20 system, which is 57.8%, indicating that the surface of the anthracite after Tween 20 adsorption is more hydrophilic. This suggests that branched surfactants have better wetting properties for potential applications compared to linear surfactants [40]. This is consistent with the abovementioned analysis conclusion.…”

Section: Interaction Energysupporting

confidence: 89%

Influence of the Branched Structure of Polyoxyethylene Units in Nonionic Surfactants on the Wettability of Anthracite: A Combined Modeling and Experimental Study

Chen

Yan

et al. 2022

Adsorption Science & Technology

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Coal dust is a significant concern to the safety of coal mine operations. The wettability of coal can be effectively altered by adding surfactants to water. The development of high-efficiency dust suppressants is hampered by a lack of understanding of the microscopic interaction process between coal dust and surfactants. In this investigation, the influence of the branched structure of the polyoxyethylene unit in nonionic surfactants on the wettability of anthracite surfaces was evaluated by combining the modeling study and experimental research. The macromolecular model of Jincheng anthracite with 55 different components (C7730H3916O133N123S25) was constructed. Lauryl polyoxyethylene ether C12(EO)20 and Tween 20 were selected. The simulation results showed that due to the branched structure of polyoxyethylene, the surface of anthracite after adsorption by Tween 20 is more hydrophilic. Further analysis found that the adsorption configuration of Tween 20 is that the hydrophilic head group covers the hydrophobic tail chain, while the adsorption configuration of C12(EO)20 is that the hydrophobic tail chain covers the hydrophilic head group. The network structure formed by Tween 20 is relatively loose, and the surface is rougher. The network structure formed by C12(EO)20 is denser. Water molecules have a higher aggregation degree near Tween 20 and stronger permeability, and more hydrogen bonds are formed. The existence state of carbon and oxygen elements on the surface of modified coal was analyzed by XPS experiment, which confirmed the adsorption structure obtained by molecular simulation.

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Section: Interaction Energysupporting

confidence: 89%

Influence of the Branched Structure of Polyoxyethylene Units in Nonionic Surfactants on the Wettability of Anthracite: A Combined Modeling and Experimental Study

Chen

Yan

et al. 2022

Adsorption Science & Technology

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“…However, it should be noted that the extraction of natural surfactants is very expensive. In this case, synthetic surfactants containing ester, amide, disulfide or other degradable moieties are a good alternative [47][48][49][50].…”

Section: Nanocontainers Based On Biodegradable Surfactantsmentioning

confidence: 99%

“…Nanocontainers based on amino acid surfactants can be used as carriers for a wide range of medicines [22,34,[41][42][43][44][45][46][47][48][49][50][51][52][53][54]. Lysine-based surfactants were obtained to improve the solubilization of water insoluble anticancer drugs [59].…”

Section: Amino Acid Surfactantsmentioning

confidence: 99%

Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability

et al. 2021

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This review focuses on key topics in the field of drug delivery related to the design of nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability, low toxicity, and the ability to overcome biological barriers. For these reasons, much attention is paid to the amphiphile-based carriers composed of natural building blocks, lipids, and their structural analogues and synthetic surfactants that are capable of self-assembly with the formation of a variety of supramolecular aggregates. The latter are dynamic structures that can be used as nanocontainers for hydrophobic drugs to increase their solubility and bioavailability. In this section, biodegradable cationic surfactants bearing cleavable fragments are discussed, with ester- and carbamate-containing analogs, as well as amino acid derivatives received special attention. Drug delivery through the biological barriers is a challenging task, which is highlighted by the example of transdermal method of drug administration. In this paper, nonionic surfactants are primarily discussed, including their application for the fabrication of nanocarriers, their surfactant-skin interactions, the mechanisms of modulating their permeability, and the factors controlling drug encapsulation, release, and targeted delivery. Different types of nanocarriers are covered, including niosomes, transfersomes, invasomes and chitosomes, with their morphological specificity, beneficial characteristics and limitations discussed.

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Synthesis and micellization of cationic trisiloxane surfactants with poly(ethylene glycol)

Tan

Zhang

2022

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Thermodynamically stable vesicle formation of biodegradable double mPEG-tailed amphiphiles with sulfonate head group

Abstract: Spontaneous vesicle formation by biodegradable novel double mPEG-tailed amphiphiles.

Cited by 3 publications

References 55 publications

Influence of the Branched Structure of Polyoxyethylene Units in Nonionic Surfactants on the Wettability of Anthracite: A Combined Modeling and Experimental Study

Influence of the Branched Structure of Polyoxyethylene Units in Nonionic Surfactants on the Wettability of Anthracite: A Combined Modeling and Experimental Study

Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability

Synthesis and micellization of cationic trisiloxane surfactants with poly(ethylene glycol)

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