Thermodynamic Properties of Solubility for Nitrophenyl Derivatives of Furfural Oxime in Organic Solvents

Abstract

Abstract. Enthalpies and entropies of dissolution in acetonitrile, propan-2-ol and ethyl acetate were determined from the results of temperature dependence of solubility for 5-(2-nitro phenyl)-2-furyl oxime, 5-(3-nitro phenyl)-2-furyl oxime and 5-(4-nitro phenyl)-2-furyl oxime. Sublimation enthalpies and entropies were determined using integral effusion Knudsen method; adjustment of these values to 298K was conducted. Using these values the thermodynamic properties of solvation in the investigated systems were calculated. The influence of physical properties of the solvent on dissolution of the investigated compounds was analyzed.Keywords: 5-(2-nitro phenyl)-2-furyl oxime, enthalpy, entropy, solubility, sublimation, solvation IntroductionHeterocyclic compounds are very common in nature. Most of them take part in biological processes. Phenyl-furanic fragment is present in a lot of substances which develop a wide range of biological activity. Lately, functional compounds with phenyl-furanic fragment are widely used in multi-component reactions that allow optimizing the resource usage and conducing the green chemistry concept. Most of the parameters for the processes of syntheses for these compounds were chosen using the method of probes and mistakes. Determination of thermodynamic properties for compounds with phenyl-furanic fragment allows to calculate energetic properties of their molecules and to decrease the energy usage at separate stages of processes of their synthesis, purification and use. Investigated in the current work furfural oximes are used as soil nitrification inhibitors [8] properties. Most processes with their participation take place in solvents. That's why thermodynamic properties of furfural oxime and its nitrophenyl derivatives solubility are needed for optimization and calculation of energy balances for processes of synthesis, purification and application of these compounds, which has become the main aim of this work.