The thermal, phase transition of carbamazepine dihydrate and the solid-state transformation of carbamazepine from form III to form I were performed by Differential scanning calorimetry (DSC), Thermo gravimetry (TG-DTA), and X-ray powder diffraction.The non-thermal kinetic analysis of carbamazepine dihydrate and form III was carried out by DSC at different heating rates in dynamic nitrogen atmosphere. The model-free model, the Kissinger method, was used to give the Arrhenius parameters. Arrhenius plots from the kinetic model yielded activation energies corresponding to dehydration of dihydrate and melting of anhydrate CBZ form I were 95.28, 966.06 kJ mol -1 , the pre-exponential factors were 8.34E?11 and 1.41E?149, respectively. For the transformation of carbamazepine from form III to form I, activation energies corresponding to the melting of CBZ form III, recrystallization of form I, and melting of form I were 1160.81, 710.89, 1265.89 kJ mol -1 , the pre-exponential factors were 2.29E?144, 4.43E?91, and 1.61E?151, respectively. As a comparison, Ozawa method was used to verify the activation energy values obtained by Kissinger method. The result shows a close activation energy values between two methods.