Thermodynamic and spectroscopic studies of copper (II) complexes with three bis(amide) ligands derived from l-tartaric acid

Tounsi, Nassera; Dupont, Laurent; Mohamadou, Aminou; Aplincourt, Michel; Plantier‐Royon, Richard; Massicot, Fabien; Harakat, Dominique; Portella, Charles

doi:10.1016/j.jinorgbio.2005.09.010

Cited by 17 publications

(8 citation statements)

References 28 publications

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“…N,N-Dipropyl tartramide (PT) was prepared according to published procedures. 19 C) nuclear magnetic resonance (NMR) spectra were obtained using a Varian 400 or 500 MHz spectrometer. Samples were dissolved in deuterated chloroform (CDCl 3 ), dimethyl sulfoxide (DMSO-d 6 ), or CD 3 OD using trimethylsilane or a deuterated solvent (DMSO-d 6 or CD 3 OD) as an internal reference.…”

Section: Methodsmentioning

confidence: 99%

“…2-Boc-AET was prepared according to modified literature procedures. 19 In brief, dimethyl tartrate (6, 2.43 mmol) was dissolved in anhydrous tetrahydrofuran (7.5 mL) under nitrogen. N-Boc-ethylenediamine (6.79 mmol) was added, and the reaction mixture was stirred at 40 °C overnight.…”

Section: Methodsmentioning

confidence: 99%

“…1,2-Dioleoyl- sn -glycero-3-phosphocholine (DOPC) and 1,2-dioleoyl- sn -glycero-3-phospho-(1′- rac -glycerol) (DOPG) were purchased from Avanti Polar Lipids, Inc. (Alabaster, AL) and used without further purification. N , N -Dipropyl tartramide (PT) was prepared according to published procedures . For broth microdilution assays, bacterial strains Escherichia coli ATCC 43895, Pseudomonas aeruginosa ATCC 14213, Listeria monocytogenes ATCC 49594, and Staphylococcus aureus Rosenbach ATCC 29213 were received from the American Tissue Culture Collection (ATCC, Manassass, VA, USA).…”

Section: Methodsmentioning

confidence: 99%

“…2-Boc-AET was prepared according to modified literature procedures . In brief, dimethyl tartrate ( 6 , 2.43 mmol) was dissolved in anhydrous tetrahydrofuran (7.5 mL) under nitrogen.…”

Section: Methodsmentioning

confidence: 99%

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Biscationic Tartaric Acid-Based Amphiphiles: Charge Location Impacts Antimicrobial Activity

Faig

Arthur²,

Fitzgerald³

et al. 2015

Langmuir

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Cationic amphiphiles have received increasing attention as antimicrobials given their unique ability to disrupt bacteria cell membranes. While extensive research has demonstrated that amphiphiles' hydrophobic-to-charge ratio significantly modulates antibacterial activity, less work has focused on elucidating the specific impact of charge location on amphiphile bioactivity. In this study, two series of cationic amphiphiles, termed bola-like and gemini-like, were synthesized with analogous hydrophobic-to-charge ratios yet differing charge location, and their resulting antibacterial activity was assessed. Bola-like amphiphiles exhibited preferential activity against two Gram-positive bacteria, with activity increasing with increasing hydrophobicity, whereas gemini-like amphiphiles were active against both Gram-positive and Gram-negative bacteria, with activity decreasing with increasing hydrophobicity. After identifying lead compounds from each amphiphile series (bola- and gemini-like), biophysical experiments indicated that both amphiphiles were membrane-active; notably, the lead gemini-like amphiphile exhibited a strong dependence on electrostatic interactions for membrane interaction. In contrast, the lead bola-like amphiphile exhibited a reliance on both hydrophobic and electrostatic contributions. These results demonstrate that charge location significantly impacts cationic amphiphiles' antibacterial and membrane activity.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…2-Boc-AET was prepared according to modified literature procedures . In brief, dimethyl tartrate ( 6 , 2.43 mmol) was dissolved in anhydrous tetrahydrofuran (7.5 mL) under nitrogen.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Biscationic Tartaric Acid-Based Amphiphiles: Charge Location Impacts Antimicrobial Activity

Faig

Arthur²,

Fitzgerald³

et al. 2015

Langmuir

View full text Add to dashboard Cite

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“…The formation constants of complexes can be calculated using several techniques such as UV-Vis spectrophotometric method, NMR, and electrochemical methods [7][8][9][10][11][12][13][14] .The advantages such as simplicity, low cost and ease to use are the main reasons of variety application of potentiometric and spectrophotometric methods. Spectrophotometric methods have been utilized as an alternative to determine stability constants of complexes with large molar absorptivities because of its high sensitivity at concentrations of substance as low as 10 -6 M. Nowadays, the spectrophotometric techniques remain largely used in this field because of the easy interpretation and handling of the spectral data.…”

Section: Methodsmentioning

confidence: 99%

Model based multi-wavelength spectrophotometric method for calculation of formation constants of phenanthrenequinone thiosemicarbazone complexes with some metallic cations

Samadi¹,

Salamati²,

Naseri³

2013

10.5267/j.ccl

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In traditional spectrophotometric determination of stability constants of complexation, it is necessary to find a wavelength at which only one of the components has absorbance without any spectroscopic interference of the other reaction components. In the present work, a simple multi-wavelength model-based method has been developed to determine stability constants for complexation reaction regardless of the spectra overlapping of components. Also, pure spectra and concentration profiles of all components are extracted using multi-wavelength model based method. In the present work spectrophotometric titration of several cationic metal ions with new synthetic ligand were studied in order to calculate the formation constant(s). In order to estimate the formation constants a chemometrics method, model based analysis was applied.

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New Water‐Soluble Au(III) Complexes with Xyloside‐Based Ligands: Synthesis, Structural Characterization, Solution Studies and Catalytic Evaluation

et al. 2023

Self Cite

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A short and convenient approach to the original xyloside-based ligands, has been achieved, using d-xylose as a starting material. The complexation properties of these ligands towards Au(III) cations were studied by different methods, such as multinuclear NMR, mass spectrometry, elemental analysis. A preliminary study using protometric titrations has been carried out in aqueous solution under various pH conditions, thus in order to investigate the binding of Au(III) cations to these ligands. Furthermore, molecular calculations were performed to obtain additional structural information. The catalytic activity of the most stable Au(III) complexes was evaluated for the homogeneous reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) in the presence of NaBH 4 .

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Thermodynamic and spectroscopic studies of copper (II) complexes with three bis(amide) ligands derived from l-tartaric acid

Cited by 17 publications

References 28 publications

Biscationic Tartaric Acid-Based Amphiphiles: Charge Location Impacts Antimicrobial Activity

Biscationic Tartaric Acid-Based Amphiphiles: Charge Location Impacts Antimicrobial Activity

Model based multi-wavelength spectrophotometric method for calculation of formation constants of phenanthrenequinone thiosemicarbazone complexes with some metallic cations

New Water‐Soluble Au(III) Complexes with Xyloside‐Based Ligands: Synthesis, Structural Characterization, Solution Studies and Catalytic Evaluation

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