Thermo/Pressure-Sensitive Self-Fixation Surgical Meshes: The Role of Adhesive Hydrogels in Interface Attachment
Sonia Lanzalaco,
Xavier Sánchez,
Carlos Alemán
et al.
Abstract:Herein, an innovative self- and pressure-adhesive biomedical
implant
was developed. Tissue adhesion was achieved with a thermosensitive
hydrogel based on poly(N-isopropylacrylamide-co-acrylamide), PNIPAAm-co-PAAm, grafted
on a substrate composed of knitted fibers of isotactic polypropylene
mesh (PP), used as surgical mesh implants. The in vitro studies, carried
out with porcine skin, showed an important role of the inclusion of
acrylamide-based comonomer (AAm) in the thermosensitive hydrogel PNIPAAm
matrix. T… Show more
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