Thermo Compression of Thermoplastic Agar-Xanthan Gum-Carboxymethyl Cellulose Blend

Abstract

There is a gap in the literature for the preparation of agar-xanthan gum-carboxymethyl cellulose-based films by thermo compression methods. The present work aims to fill this gap by blending the polysaccharides in a plastograph and preparation of films under high pressure and temperature for a short duration of time. The pivotal aim of this work is also to know the effect of different mixing conditions on the physical, chemical, mechanical and thermal properties of the films. The films are assessed based on results from microscopic, infrared spectroscopic, permeability (WVTR), transmittance, mechanical, rheological and thermogravimetric analysis. The results revealed that the mixing volume and mixing duration had negative effects on the films’ transparency. WVTR was independent of the mixing conditions and ranged between 1078 and 1082 g/m2.d. The mixing RPM and mixing duration had a positive effect on the film tensile strength. The films from the blends mixed at higher RPM for a longer time gave elongation percentage up to 78%. Blending also altered the crystallinity and thermal behavior of the polysaccharides. The blend prepared at 80 RPM for 7 min and pressed at 140 °C showed better percent elongation and light barrier properties.

The Effect of The Topical Application of Eurycoma Longifolia Jack (TA) Root Extract Hydrogel on Vascular Endothelial Growth Factor (VEGF) Expression During Wound Healing in vivo Excisional Wound Model

“…There is also a great possibility that the availability of glycosaminoglycans in the chemical structure of xanthan gum, as it is a natural polysaccharide, might be one of the reasons for the positive effects of both TA and vehicle hydrogels. 38,[41][42][43] Therefore, these results are in agreement with published reports of many in vitro and in vivo studies that have claimed the positive effect of medicinal plants in significant upregulation of VEGF and enhancing the wound healing process via promoting angiogenesis. 8,11,36…”