Abstract:Background: Telomeric DNA is found at the end of eukaryotic chromosomes, where they play a role in protecting the chromosome and the integrity of the genome of the organism through the activity of telomerase. Saccharomyces cerevisiae exists in two genotypes: haploid and diploid. Temperature sensitive point mutation on the cdc13 gene of each genotype and deletion of exo1 gene (cdc13-1Exo1 mutants) give rise to mutant survivors at enhanced temperatures. The mode of inheritance of the thermal tolerance allele in… Show more
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