“…Research in the field of radiation biology and radiation oncology is particularly important. In 1987, on the basis of the results of the experimental, technical, and preclinical studies on BNCT of melanoma [ 11 , 12 , 13 , 14 , 15 , 16 , 17 ], Mishima et al applied BNCT with BPA for the first time in a patient with metastatic melanoma and obtained good local control of the tumor. Since then, until 2002, a total of 22 patients with melanoma were treated with BNCT [ 3 , 4 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ], which provided good tumor control and longer patient survival.…”