Thermal Field-Flow Fractionation (ThFFF)

Impact of Electron Beam Irradiation on Thermoplastic Polyurethanes Unraveled by Thermal Field-Flow Fractionation

“…21 For this study we have chosen ThFFF since this separation technique can be highly selective for changes in the polymer's topology [22][23][24] and/or chemical composition. [25][26][27][28][29] Details on the basic separation principle are given elsewhere 21,30 and in the supporting information (SI, section 1). FFF is usually coupled to a series of detectors (MALS, dRI, UV, online dynamic scattering or offline FTIR), [31][32][33][34][35] though, the analysis of the separation itself contains already useful information.…”

Dealing with the complexity of conjugated and self‐assembled polymer‐nanostructures using field‐flow fractionation

“…As already alluded to, in addition to size and chemical composition, ThFFF has shown significant sensitivities towards differences in microstructure, tacticity, architecture, thermosensitivity, and morphology. 9 Therefore, the prospect of coupling ThFFF with D5 for the analysis of PBCNs appears more favorable for the separation of complex nanostructures with multiple sensitivities. However, a few reports are available on ThFFF under aqueous conditions since the commercially available nickel‐plated ThFFF channels are prone to acidic degradation.…”

“…FFF represents a contemporary and much friendlier separation analogue for such nanostructures, by employing fluid flow dynamics and external force fields for effective separations at steady‐state conditions within a solvent filled channel. 9 Downstream, subsequent to FFF separations, a combination of multiple detectors and hyphenated techniques are available to derive invaluable information on average molar masses (M w and M n ), size, shape and morphology, degree of functionalization and aggregation, chemical composition and structure, and the distributions thereof. Additionally, FFF separations inherently make provisions prior to characterization for the simplification of complex sample matrices containing byproducts, contaminants and unreacted materials.…”