Thermal conduction in a harmonic chain coupled to two cavity-optomechanical systems

He, Ziqiang; Dong, Guangjiong

doi:10.1103/physreva.103.053509

Cited by 2 publications

(3 citation statements)

References 79 publications

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“…According to a report, the cell diameter is much larger than the laser wavelength and smaller than the beam width, so the gradient force can be ignored . The following formula showed that light force is closely related to cell size and RI. , P is the power incident onto the microsphere’s cross-sectional area S ( S = π b 2 , and b is the cell radius), Q is the radiation pressure coefficient ( Q is positively correlated with the refractive index of cell), and c is the speed of light …”

Section: Resultsmentioning

confidence: 99%

“…44 The following formula showed that light force is closely related to cell size and RI. 49,50 P is the power incident onto the microsphere's cross-sectional area S (S = πb 2 , and b is the cell radius), Q is the radiation pressure coefficient (Q is positively correlated with the refractive index of cell), and c is the speed of light. 45 Scheme 1 shows how PS microspheres used in the optofluidic system can achieve accurate separation of CTCs without contact based on light force.…”

Section: Resultsmentioning

confidence: 99%

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Noninvasive Optical Isolation and Identification of Circulating Tumor Cells Engineered by Fluorescent Microspheres

Chen

Guo

Zhao

et al. 2022

ACS Appl. Bio Mater.

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Circulating tumor cells (CTCs) are rare, meaning that current isolation strategies can hardly satisfy efficiency and cell biocompatibility requirements, which hinders clinical applications. In addition, the selected cells require immunofluorescence identification, which is a time-consuming and expensive process. Here, we developed a method to simultaneously separate and identify CTCs by the integration of optical force and fluorescent microspheres. Our method achieved high-purity separation of CTCs without damage through light manipulation and avoided additional immunofluorescence staining procedures, thus achieving rapid identification of sorted cells. White blood cells (WBCs) and CTCs are similar in size and density, which creates difficulties in distinguishing them optically. Therefore, fluorescent PS microspheres with high refractive index (RI) are designed here to capture the CTCs (PS-CTCs) and increase the average index of refraction of PS-CTCs. In optofluidic chips, PS-CTCs were propelled to the collection channel from the sample mixture, under the radiation of light force. Cells from the collection outlet were easily identified under a fluorescence microscope due to the fluorescence signals of PS microspheres. This method provides an approach for the sorting and identification of CTCs, which holds great potential for clinical applications in early diagnosis of disease.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Noninvasive Optical Isolation and Identification of Circulating Tumor Cells Engineered by Fluorescent Microspheres

Chen

Guo

Zhao

et al. 2022

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…Unlike most experimental platforms having been utilized for studying nonequilibrium thermodynamics, which use only one mechanical resonator, the two-membrane cavity optomechanical system allows researchers to investigate the situations where the nonequilibrium state is driven by thermal gradient, as well as nonequilibrium thermodynamic theories, such as fluctuation theorems and thermodynamics uncertainty relations [67] , with interacting subsystems, particularly in the strong coupling regime. Although some nonequilibrium phenomena could be demonstrated using multiple modes of a single mechanical resonator [64] , a two-membrane system not only offers more degrees of freedom to control, such as individual mechanical frequency and optomechanical coupling strength, but can also be straightforwardly extended to optomechanical arrays, which is crucial for investigating effects such as Fourier's law [68] and Frohlich condensate of phonons [69] .…”

Section: Heat Transfermentioning

confidence: 99%