Thermal characteristics of microwave ablation in the vicinity of an arterial bifurcation

Liu, Youjun; Qiao, Aike; Nan, Qun; Yang, Xiaoyong

doi:10.1080/02656730600905686

Cited by 22 publications

(8 citation statements)

References 15 publications

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“…Cancer treatment using hyperthermia necessitates the generation of an adequately controlled amount of heat inside the cancerous tumor. If it is exposed to a temperature of approximately 52 • C for one hour, the cancer tissue can be damaged [7][8][9][10][11]. The amount of dissipated heat should be used prudently.…”

Section: Introductionmentioning

confidence: 99%

Numerical Analysis of Human Cancer Therapy Using Microwave Ablation

2019

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Microwave ablation is one type of hyperthermia treatment of cancer that involves heating tumor cells. This technique uses electromagnetic wave effects to kill cancer cells. A micro-coaxial antenna is introduced into the biological tissue. The radiation emitted by the antenna is absorbed by the tissue and leads to the heating of cancer cells. The diffuse increase in temperature should reach a certain value to achieve the treatment of cancer cells but it should be less than a certain other value to avoid damaging normal cells. This is why hyperthermia treatment should be carefully monitored. A numerical simulation is useful and may provide valuable information. The bio-heat equation and Maxwell’s equations are solved using the finite element method. Electro-thermal effects, temperature distribution profile, specific absorption rate (SAR), and fraction of necrotic tissue within cancer cells are analyzed. The results show that SAR and temperature distribution are strongly affected by input microwave power. High microwave power causes a high SAR value and raises the temperature above 50 °C, which may destroy healthy cells. It is revealed that with a power of 10 W, the tumor cells will be killed without damaging the surrounding tissue.

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Section: Introductionmentioning

confidence: 99%

Numerical Analysis of Human Cancer Therapy Using Microwave Ablation

2019

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“…Heat transfer due to blood flow in large vessels near tumors should be taken into account during planning of treatments with theoretical models. One method for doing so is to specify an effective convective heat transfer coefficient along the vessel surface [58, 59]. A more complete analysis incorporates the complex relationship between blood flow dynamics in the vessel and transient temperature [60].…”

Section: Physical Phenomena During Microwave Tissue Ablationmentioning

confidence: 99%

“…The impact of blood vessel cooling may be explored using a convective boundary condition on the vessel boundary, as has been done for RFA. A more accurate model would use the approach of [59] and include a coupled fluid flow model to explore the impact of various flow profiles on the ablation zone.…”

Section: Current Challenges and Research Trendsmentioning

confidence: 99%

Theoretical Modeling for Hepatic Microwave Ablation~!2009-10-21~!2009-12-30~!2010-02-04~!

Prakash¹

2010

TOBEJ

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Thermal tissue ablation is an interventional procedure increasingly being used for treatment of diverse medical conditions. Microwave ablation is emerging as an attractive modality for thermal therapy of large soft tissue targets in short periods of time, making it particularly suitable for ablation of hepatic and other tumors. Theoretical models of the ablation process are a powerful tool for predicting the temperature profile in tissue and resultant tissue damage created by ablation devices. These models play an important role in the design and optimization of devices for microwave tissue ablation. Furthermore, they are a useful tool for exploring and planning treatment delivery strategies. This review describes the status of theoretical models developed for microwave tissue ablation. It also reviews current challenges, research trends and progress towards development of accurate models for high temperature microwave tissue ablation.

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“…The Pennes equation works well with acceptable accuracy in the absence of large blood vessels. 7 A method to account for the heat sink effect that is caused by large blood vessels would be to specify an effective convective heat transfer coefficient along the vessel surface 8,9 or to include some complex relationship between blood flow dynamics in the vessel and transient temperature. 10 However, it is widely accepted that despite the development of more complex and rigorous models of heat transfer within a tissue, 11 the Pennes equation remains a remarkably effective method for modeling heat transfer in tissue during thermal ablation.…”

Section: Introductionmentioning

confidence: 99%

Real-time tumor ablation simulation based on the dynamic mode decomposition method

Bourantas¹,

Ghommem²,

Kagadis³

et al. 2014

Med. Phys.

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30Purpose: The Dynamic Mode Decomposition (DMD) method is used to provide a reliable forecasting of tumor ablation treatment simulation in real time, which is quite needed in medical practice. To achieve this, an extended Pennes bioheat model must be employed, taking into account both the water evaporation phenomenon and the tissue damage during tumor ablation. 35Methods: A meshless point collocation solver is used for the numerical solution of the governing equations. The results obtained are used by the DMD method for forecasting the numerical solution faster than the meshless solver. The procedure is first validated against analytical and numerical predictions for simple problems. The DMD method is then applied to three-dimensional simulations that involve modeling of tumor ablation and 40 account for metabolic heat generation, blood perfusion, and heat ablation using realistic values for the various parameters. Results:The present method offers very fast numerical solution to bioheat transfer, which is of clinical significance in medical practice. It also sidesteps the mathematical treatment of boundaries between tumor and healthy tissue, which is usually a tedious procedure with 45 some inevitable degree of approximation. The DMD method provides excellent predictions of the temperature profile in tumors and in the healthy parts of the tissue, for linear and non-linear thermal properties of the tissue. Conclusions:The low computational cost renders the use of DMD suitable for in-situ real time tumor ablation simulations without sacrificing accuracy. In such a way the tumor 50 ablation treatment planning is feasible using just a personal computer thanks to the simplicity of the numerical procedure that is used. The geometrical data can be provided directly by medical image modalities used in everyday practice

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Thermal characteristics of microwave ablation in the vicinity of an arterial bifurcation

Abstract: It can be concluded that inadequate ablations can be the result not only from a close proximity between the antenna and the blood vessel, but also from a complicated blood flow in large vessels whose structure causes recirculation flow.

Cited by 22 publications

References 15 publications

Numerical Analysis of Human Cancer Therapy Using Microwave Ablation

Numerical Analysis of Human Cancer Therapy Using Microwave Ablation

Theoretical Modeling for Hepatic Microwave Ablation~!2009-10-21~!2009-12-30~!2010-02-04~!

Real-time tumor ablation simulation based on the dynamic mode decomposition method

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