Thermal Burn Injury from a Wedding Ring: An Unusual Case

Andrade, Peter; Kaura, Arminder; Bryant, Justin R.; Burke, Edward F.

doi:10.1016/j.jccw.2018.06.004

Cited by 3 publications

(3 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Macroscopic, microscopic, and electron microscopic studies of the atria and auricles of intact guinea pigs have shown that they have general features of structure [13,14]. Complex studies have shown that the nature and degree of damage of the parts of the heart depended on the duration of the experiment and increased according to the stages of thermal trauma [15].…”

Section: Methodsmentioning

confidence: 99%

Microscopic and submicroscopic structure of the heart atria and auricles in condition of the experimental thermal trauma

2020

Biointerface Res Appl Chem

View full text Add to dashboard Cite

Burns is the damage of the skin or mucous membranes (often with underlying tissues), because of high-temperature influence (thermal burns), chemical, electrical, radiation, combined, thermochemical and electrothermal factors influence. According to the investigations, burns rank third among other injuries, and in some countries, second, second only to transport injuries. Although the level of survival after burns is increasing, the problem of their treatment remains relevant in modern medicine and pharmacy. The aim was to study the peculiarities and the patterns of morphofunctional changes in the structural components of the heart atria and auricles in case of the experimental thermal trauma. The study involves 30 adult guinea pigs with a bodyweight of 630-670 g. The burn was applied under general ether anesthesia with water vapor at a temperature of 96-97 0C on the surface of the skin of the animal's back for 60 seconds. The size of the lesion area was 18-20% of the body surface. The depth of the lesion corresponded to the degree ІІІА -IIIB. The experimental animals were divided into two groups: the first - intact guinea pigs (6 heads); second - animals with thermal trauma (24 heads). Were used a number of methods of investigation, including macrometric and massometric - to establish the structural restructuring of the heart and its parts, microscopic and electron microscopic to detect changes in the structural components of the atrium and auricle of the heart; morphometric - to obtain quantitative parameters of the morphological components of the heart; mathematical and statistical - to ensure the analysis of the reliability of the research results. In intact guinea pigs, the morphological organization of the heart auricles differs from the atria by the direction of the muscle fibers, the ratio of morphometric parameters of their structural components and the content of muscle endocrine cells. Submicroscopically, endocrine myocytes of the auricles of the heart contain more hormonal granules than atria. In the ears of the heart, the relative volume of connective tissue is 1,34 times greater, and the relative volume of muscle fibers is 1,03 times smaller than in the atria. Submicroscopically, endocrine muscle cells of the heart auricle contain more hormonal granules than atria. It has been established that thermal trauma causes significant morphofunctional changes in the atria and auricles of the heart at different levels of their structural organization. The degree of damage depends on the duration of the experiment and develops against the background of increased plasma toxicity. In the stages of burn shock and early toxemia, adaptive-compensatory processes develop in the structures of the heart, and irreversible destructive changes occur in the stages of late toxemia and septicotoxemia.

show abstract

Section: Methodsmentioning

confidence: 99%

Microscopic and submicroscopic structure of the heart atria and auricles in condition of the experimental thermal trauma

2020

Biointerface Res Appl Chem

View full text Add to dashboard Cite

show abstract

“…Electrical or chemical hand injuries are associated with high morbidity. Generally, second or third-degree hand burns are considered a major burn injury, and it is mandatory to refer them to the burn center [1][2][3]. Contracture following hand burns is common, and movement limitations could decrease quality of life, significantly.…”

Section: Introductionmentioning

confidence: 99%

Untitled

2022

J. Med. Chem. Sci.

View full text Add to dashboard Cite

Ring burns are often circumferential, increasing the chance of compartment syndrome and ischemia distal to the injury site. The burn size is usually small. However, sometimes injury management may be difficult or threaten the limb, leading to amputation. Different effective treatment methods include conservative therapy, grafting, flap surgery, or amputation. This study reports the therapeutic management of two patients with ring burn Injury. Two patients with ring burn injuries who were admitted to the burn ward were treated with initial surgical debridement and full-thickness skin grafts. At the same time, one of them underwent the advancement flap technique by adjacent tissue recruitment. Even though patients waited up to 3 weeks before the operation, they underwent Surgery immediately after admission, and the long-term result was excellent, and acceptable. So, training of medical staff and efforts to prevent ring burn injury is highly recommended.

show abstract

“…The term recovery of the burned skin determines the course of burn disease, the formation of complications, the cosmetic effect. It is known that deep and large thermal burns are not limited only to local damages of tissues, but also cause significant violations of all systems and organs, metabolic processes in the body [1,2,4,6]. The primary link in the pathogenesis of burn disease is the destruction of the skin, significant hemodynamic disorders and violation of neuroendocrine regulation [6,12,14].…”

Section: Introductionmentioning

confidence: 99%

Morphometric studies of the damaged skin area after experimental thermal trauma and during correction with a cryo-lyophilized xenograft skin substrate

2018

View full text Add to dashboard Cite

According to WHO, burns rank third place among other injuries, and in some countries, the second, after traffic injuries. One of the promising tools for treating burn wounds is the use of lyophilized xenograft skin substrate. The purpose of this work was to determine the morphometric parameters of the affected by burns area of the skin in the dynamics after an experimental thermal trauma and in the case of correction by crushed lyophilized xenograft skin substrate. Burning of third degree on the shaved skin of the back of the guinea pig was applied to the vapor under general anesthetic. Morphometrically, at 7, 14, and 21 days of the experiment, the thickness of the epidermis (thin skin without a layer of scales), the number of fibroblast cells per unit area, the outer and inner diameter of the capillaries were determined in the boundary and central areas of the wound. Morphometric studies were carried out using programs VideoTest-5.0, KAAPA Image Base and Microsoft Exсel on a personal computer. Statistical processing of the obtained quantitative data was carried out using methods of variation statistics with the determination of the mean arithmetic and its error (M±m), Student’s criterion (t) and reliability index (p). Differences are considered valid at р≤0.05. It has been established that already in the 7 day of the experiment, under conditions of wound closure by xenograft skin substrate marked a significant thickening of the epidermis on the periphery of the wound appear. Activation of the process of boundary epithelization contributes to the renewal of components of the microcirculatory bed, the formation of granulation tissue. It was found that on the 14 day of application of the corrective factor in the peripheral zone of the wound, the number of cells of the fibroblast row and the mean value of the thickness of the epidermis reach their peak value, significantly (p<0.001) exceeding such indices of animals in intact group and group of animals without correction. The morphometric parameters of capillaries in this period of the experiment indicate a good development of the microcirculation, which improves regional epithelization. On the 21 day of the experiment, under the condition of correction, the border between the regional and central parts of the wound is almost lost. Thus, the results of morphometric studies indicate that the use of cryo-lyophilized xenograft skin substrate after a thermal trauma of the skin contributes to the healing of the wound defect with the formation of connective tissue of the dermis, angiogenesis, and complete epithelization of the surface of the affected epidermis layer.

show abstract

Thermal Burn Injury from a Wedding Ring: An Unusual Case

Cited by 3 publications

References 6 publications

Microscopic and submicroscopic structure of the heart atria and auricles in condition of the experimental thermal trauma

Microscopic and submicroscopic structure of the heart atria and auricles in condition of the experimental thermal trauma

Untitled

Morphometric studies of the damaged skin area after experimental thermal trauma and during correction with a cryo-lyophilized xenograft skin substrate

Contact Info

Product

Resources

About