Thermal behavior of PLA and calcium phosphate compositions

Evaluation of the Bioactive Properties of the Mineral-Polymer Composite Calcium Phosphates – Polylactide

“…A mixture of calcium phosphates obtained by precipitation according to a previously developed method [9,12], including about 60% 4 hydroxyapatite, about 15% amorphous HAP, about 15% carbonate-substituted HAP, and about 10% b-tricalcium phosphate (TCP), was used as the mineral component of the composite material (MCC). The specific surface area of the MCC, determined by the Brunauer-Emmett-Teller (BET) method, was equal to 4.8 m 2 /g (Sorptometer S1).…”

“…In [4,8] PLA-based composites with up to 40 wt.% mineral component in the form of hydroxyapatite are shown to exhibit in vitro bioactivity. In contrast to ceramics, composites containing more than 45 wt.% of a mineral component are close in terms of mechanical properties to natural bone [9]. Owing to the polymer they are thermoplastic, which is a great advantage, because it opens up the possibility of molding articles of almost any shape using 3D printing [10].…”

3D printing of PLA:CaP:GO scaffolds for bone tissue applications

“…11 Several works have obtained 3D porous scaffolds combining PLA and CaP by traditional methodologies, such as solvent-casting or phaseseparation, as in the research published by Charles-Harris et al (2008), 12 indicating their biocompatibility in vitro and the relevance of the nal architecture on the cell's behaviour. In relation to this last aspect, the advantages provided by the additive manufacturing to fabricate customised 3D structures, controlling the geometry and inner architecture of the structure, has promoted several authors to investigate the obtaining of PLA scaffolds, 13 CaP scaffolds 14,15 or combination of both 16 using this 3D printing technology. Thus, for instance, in the particular case of Nevado et al (2020) a lament of PLA-CaP composite was obtained by hot-melt extrusion to be then used in a lament printer.…”