Thermal behavior and thermodynamic parameters of some complexes of biologically active nucleic acid constituents

Abstract

The thermal behavior of some complexes derived from biologically nucleic acid constituents has been studied applying differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) techniques. Thermodynamic parameters, decompositions and thermal stabilities are calculated and explained. All the complexes gave exothermic peaks with -ve signs for change of entropy values, ΔS which indicate that the activated transition states are more ordered, i.e. in a less random molecular configuration than the reacting complexes. TGA gives the mechanism of decomposition.