Thermal and spectroscopic characterization of several derivatives containing a new organic ring system

Abstract

Several derivatives containing a new organic ring system, the tropane-6-spiro-5'-hydantoin structure (namely 8-alkyl-8-azabicyclo [3.2.1.] octane-6-spiro-5'-imidazoline-2',4'-diones) have been characterized by thermal (DSC and simultaneous DTA-TG-DTG) and spectroscopic techniques (IR, IH-NMR, 13C-NMR). X-ray powder diffraction and elemental analysis were applied for structural and molecular characterization. All the compounds melt in the range 160-250~ and undergo decomposition with progressive mass loss after the solid-liquid thermal transition with molecular degradation. It was found that tropane-6-spiro-5'-hydantoin derivatives with the hydantoin ring in i3 position are thermally less stable than those containing this ring in c~ position.