There are at least three genetically distinct small piroplasms from dogs

Kjemtrup, Anne; Kocan, A. Alan; Whitworth, Lisa; Meinkoth, James H.; Birkenheuer, Adam J.; Cummings, Jean Bruce; Boudreaux, Mary K.; Stockham, S. L.; Irizarry-Rovira, Armando R.; Conrad, Patricia A.

doi:10.1016/s0020-7519(00)00120-x

Cited by 128 publications

(87 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1) and previous work with this gene region and some of the same taxa we examined (Allsopp et al, 1994;Kjemtrup et al, 2000;), these are not discordant topologies. For example, Kjemtrup et al (2000) found that C. felis was a member of a clad containing six representatives of Theileria whereas our analysis suggests that the sister-group relationship of C. felis and the unknown Pallas's cat organism are sister to a clad containing four representatives of Theileria and three rep-resentatives of Babesia. However, based on our analysis, the relationship among Theileria, Babesia, C. felis, and the unknown Pallas's cat organism are part of an unresolved polytomy.…”

supporting

confidence: 77%

“…Although we were only able to obtain sequences from a single animal, if rates of evolution of this piroplasm in Pallas's cats is similar to rates of evolution of closely related piroplasms, we suspect that additional representatives of this organism from additional cats would not alter our conclusions. Supporting this assumption is the findings of Kjemtrup et al (2000) who examined B. gibsoni from North Carolina (USA), Oklahoma, and Japan and determined no sequence differences among these three geographically separated isolates. Nevertheless, differentiation of one taxon from another cannot be justified by the characterization of piroplasms from only one individual.…”

mentioning

confidence: 95%

“…A second indicator of support against possible conspecificity is the absolute level of genetic differentiation between the unknown Pallas's cat piroplasm in comparison with other related parasites for which species status in accepted (Zahler et al, 1998;Kjemtrup. et al, 2000).…”

mentioning

confidence: 99%

See 2 more Smart Citations

An Intraerythrocytic Small Piroplasm In Wild-caught Pallas's Cats (Otocolobus manul) from Mongolia

Ketz-Riley

Reichard

Bussche

et al. 2003

Journal of Wildlife Diseases

View full text Add to dashboard Cite

During the quarantine examination of four Pallas's cats (Otocolobus manul) imported from Mongolia in October and December 2000, intraerythrocytic piroplasms were detected on Wright-Giemsa stained blood films that were morphologically indistinguishable from other small piroplasms of felids. Further characterization of this unknown organism via polymerase chain reaction amplification, sequencing of a portion of the 18S nuclear small subunit rRNA gene, and comparisons with orthologous sequences from other piroplasms, revealed similarity to Cytauxzoon felis. This is the first report of naturally occurring erythroparasitemia in Pallas's cats and the first documented case of naturally occurring piroplasm infections in a free-ranging felid from Mongolia.

show abstract

supporting

confidence: 77%

mentioning

confidence: 95%

See 1 more Smart Citation

An Intraerythrocytic Small Piroplasm In Wild-caught Pallas's Cats (Otocolobus manul) from Mongolia

Ketz-Riley

Reichard

Bussche

et al. 2003

Journal of Wildlife Diseases

View full text Add to dashboard Cite

show abstract

“…The most important ticktransmitted infections that cause severe clinical illness in South African dogs are babesiosis (Collett, 2000) and ehrlichiosis (Rautenbach et al, 1991;Van Heerden, 1982). Babesia parasites of dogs can be grouped into two groups based on morphology (Kuttler, 1988): the large babesias, known as the Babesia canis group (Uilenberg et al, 1989) and the small babesias, which include the Babesia gibsoni group, Babesia conradae and Theileria annae (Kjemtrup et al, 2000;Kjemtrup et al, 2006;Zahler et al, 2000). The large babesias of dogs have a wide distribution which includes South Africa (Uilenberg et al, 1989), while the small babesias of dogs occur in South-East Asia, North-East Africa, Spain and the USA (Kjemtrup et al, 2000(Kjemtrup et al, , 2006Zahler www.elsevier.com/locate/vetpar Available online at www.sciencedirect.com Veterinary Parasitology 155 (2008) 152-157 et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Molecular detection of tick-borne protozoal and ehrlichial infections in domestic dogs in South Africa

Matjila¹,

Leisewitz²,

Jongejan³

et al. 2008

Veterinary Parasitology

View full text Add to dashboard Cite

A total of 1138 blood specimens were collected over a 6-year period (2000)(2001)(2002)(2003)(2004)(2005)(2006) from domestic dogs in South Africa. Specimens from domestic dogs were obtained from the Onderstepoort Veterinary Academic Hospital (OVAH) in Pretoria, the Society for the Prevention of Cruelty to Animals (Johannesburg, Durban, East London and Bloemfontein) and private practices from four provinces (Gauteng, Mpumalanga, KwaZulu-Natal and Western Cape). All specimens were screened for Babesia, Theileria, Hepatozoon and Ehrlichia/Anaplasma species using PCR and Reverse Line Blot (RLB) assays. On RLB, 560/1137 domestic dog-specimens were positive for one or more parasites. Of the positive domestic dog-specimens, 420 (75%) were infected with Babesia rossi; 82 (15%) dogs were infected with Theileria sp. (dog); 18 (3%) dogs were infected with Babesia vogeli; 14 (3%) specimens were infected with Ehrlichia canis. Mixed infections were also found: B. rossi and E. canis were detected in 12 (2%) specimens; B. vogeli and E. canis occurred in 7 (1%) specimens; Theileria sp. (dog) and E. canis in 3 (0.5%) specimens; B. rossi and B. vogeli in one specimen. B. rossi, B. vogeli and E. canis occurred simultaneously in one dog. There was also one incidental finding of a dog positive for Trypanosoma congolense. The results indicate that a wide range of tick-borne pathogens are circulating in the canine populations in South Africa. #

show abstract

“…Canine piroplasms have historically been classified as "large babesia" (Babesia canis) and "small babesia" (Babesia gibsoni) based on the size of their intraerythrocytic forms. Phylogenetic analysis of DNA sequences derived from the polymerase chain reaction (PCR) amplification of ribosomal genes has allowed further subvidision [10] of these taxa. Small Babesia now include two strains of Babesia gibsoni: "Asia" and "California", and a recently identified small Babesia [3,4,23], which is more closely related to Babesia microti than to Babesia gibsoni and has been tentatively referred to as Babesia annae [6].…”

Section: Introductionmentioning

confidence: 99%

Serum protein response and renal failure in canine Babesia annae infection

Camacho¹,

Guitian

Pallas

et al. 2005

Vet. Res.

View full text Add to dashboard Cite

-Babesia annae piroplasms have recently been recognised as a cause of infection and disease among dogs in Europe. The pathogenesis and clinical implications of this emerging disease remain poorly understood. We conducted this study to describe the electrophoretic profiles associated with the infection and to determine if B. annae associated azotaemia is caused by renal failure. We examined by microscopy 2 979 canine blood samples submitted to a diagnostic laboratory in NW Spain between September 2001 and April 2002. Small ring-shaped piroplasms were detected in blood smears of 87 samples and the identity of 58 of these presumptive cases were confirmed by PCR. This group of 58 infected dogs and a reference group of 15 healthy non-infected dogs were our study population. For all the dogs, serum protein response to -albumin, alpha-1 globulin, alpha-2 globulin, beta globulin and gamma globulin-was measured by capillary electrophoresis. The response of infected and non-infected dogs was compared and within infected dogs, the response of those with azotaemia (19) was compared with that of non-azotaemic dogs (39). Infected dogs presented a significant elevation of total proteins and all the different globulin fractions, and significantly lower levels of albumin compared to non-infected dogs. Among infected dogs, those presenting azotaemia had significantly lower concentrations of total proteins, albumin, beta and gamma globulins, and significantly higher values of alpha-2 globulin. Specific gravity was below the threshold of 1 025 for all dogs with azotaemia for which a urine sample was available (7) suggesting that azotaemia, in these dogs was of renal origin. Azotaemic dogs had higher concentrations of cholesterol and triglycerides, probably as a result of a liver compensatory response to the loss of proteins. We conclude that serum protein response in B. annae infected dogs corresponds to the pattern of a haemolytic syndrome with intense inflammatory reaction and that the azotaemia associated to the infection is very likely of renal origin. serum proteins / Babesia annae / azotaemia / renal failure

show abstract

There are at least three genetically distinct small piroplasms from dogs

Cited by 128 publications

References 22 publications

An Intraerythrocytic Small Piroplasm In Wild-caught Pallas's Cats (Otocolobus manul) from Mongolia

An Intraerythrocytic Small Piroplasm In Wild-caught Pallas's Cats (Otocolobus manul) from Mongolia

Molecular detection of tick-borne protozoal and ehrlichial infections in domestic dogs in South Africa

Serum protein response and renal failure in canine Babesia annae infection

Contact Info

Product

Resources

About