Therapy for Foetal Pericardial Tumours: Survival following in utero Shunting, and Literature Review

Devlieger, Roland; Hindryckx, An; Mieghem, Tim Van; Debeer, Anne; Catte, Luc De; Gewillig, Marc; Gucciardo, Léonardo; Deprest, Jan; Meyns, Bart

doi:10.1159/000236156

Cited by 27 publications

(23 citation statements)

References 77 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Twenty-one (38.2 %) fetuses had critical or severe conditions in utero or after delivery: fetal/neonatal respiratory distress (n = 12) [12-14, 19, 21, 22, 29, 33, 34, 38, 50], cardiac tamponade (n = 3) [16,17,23], fetal arrest (n = 3) [11,37,46], dyspnea (n = 2) [27,39], and tachypnea (n = 1) [38].…”

Section: Resultsmentioning

confidence: 99%

Fetal Intrapericardial Teratomas: An Update

Yuan

2020

Z Geburtshilfe Neonatol

View full text Add to dashboard Cite

Fetal intrapericardial teratomas are rare and benign cardiac tumors. By comprehensive literature retrieval of the pertinent articles published since 2000, 49 articles with 61 cases of intrapericadial teratomas were recruited into this study. The intrapericardial teratomas were found during pregnancy in 55 cases (fetal group), while the tumors were detected until neonatal period in 6 cases (neonatal group). In the fetal group, 15 cases were critical with fetal/neonatal respiratory distress or cardiac tamponade. Antenatal treatments including centesis, shunt placement, open fetal surgery and the ex utero intrapartum treatment were required in 24 (43.6%) fetal cases. Postnatal intubation was required in 19 cases with 18 of them having immediate intubation after birth. Postnatal tumor resection was performed in 41 (95.3%) cases. In neonatal group, 4 neonates had respiratory distress and/or cardiac tamponade. Neonatal intubation was required in 1 (16.7%) patient. Surgical tumor resection was performed in all 6 patients. A comparison between the fetal and neonatal groups revealed that the fetal group was associated with higher refractory effusions while the neonatal group had a higher incidence of respiratory distress. Although the all cause death rate was higher in the fetal group than in the neonatal (25.5 vs. 0%), but lack of a statistical significance. Antenatal treatments for fetal intrapericardial teratomas are feasible but carry higher risks in comparison to neonatal cases.

show abstract

Section: Resultsmentioning

confidence: 99%

Fetal Intrapericardial Teratomas: An Update

Yuan

2020

Z Geburtshilfe Neonatol

View full text Add to dashboard Cite

show abstract

“…However, there is only scarce data regarding this procedure in the literature and it is highly [8,17]. Table I [8,17], two cases underwent pericardioamniotic shunting [9,10] and one case underwent thoracoamniotic shunting following pericardiocentesis [7]. In others, single or serial pericardiocentheses were performed for hydrops or tamponade or large pericardial effusion [3,4,6,8,12,15,16,[18][19][20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Successful intrauterine treatment of nonimmune hydrops fetalis due to pericardial tumor

Esmer¹,

Bornaun²,

Bakirci³

2019

Marmara Medical Journal

View full text Add to dashboard Cite

The prenatal diagnosis of pericardial tumor is extremely rare. It may have serious consequences such as massive pericardial effusion, cardiac tamponade, hydrops fetalis and fetal demise. We present a case of nonimmune hydrops fetalis secondary to pericardial mass which was successfully treated in utero by serial pericardiocentesis. Also, we present a review of the literature regarding the intrauterine interventions performed in pericardial tumor cases. At 24 weeks' gestation ascites, diffuse subcutaneous edema at the thorax and abdomen, scalp edema and two masses within severe pericardial effusion were detected. After the pericardiocentesis performed at 25, 28 and 29 weeks' gestation, ascites and scalp edema resolved, and the pericardial effusion regressed gradually. The size of masses did not change throughout the gestation. After the infant was born at 37 weeks' gestation, the masses shrunk spontaneously within five months.

show abstract

“…Thereby, we identified 5 cases with pericardial teratoma in which a pericardio-amniotic shunt was successfully placed [5,6,7,8,9]. One fetus died in utero 8 days after the intervention and one died due to premature delivery 1 1 / 2 weeks after the intervention.…”

Section: Discussionmentioning

confidence: 99%

Pericardio-Amniotic Shunting for Incomplete Pentalogy of Cantrell

et al. 2017

View full text Add to dashboard Cite

A 27-year-old woman, gravida 2, para 0, presented with an incomplete Pentalogy of Cantrell with an omphalocele, diaphragmatic hernia, and a pericardial defect at 32 weeks' gestation. A large pericardial effusion compressed the lungs and had led to a reduced lung growth with an observed-to-expected total lung volume of 28% as measured by MRI. The effusion disappeared completely after the insertion of a pericardio-amniotic shunt at 33 weeks. After birth, the newborn showed no signs of pulmonary hypoplasia and underwent a surgical correction of the defect. Protracted wound healing and a difficult withdrawal from opioids complicated the neonatal period. The child was discharged on postnatal day 105 in good condition. This case demonstrates that in case of Pentalogy of Cantrell with large pericardial effusion, the perinatal outcome might be improved by pericardio-amniotic shunting.

show abstract

Therapy for Foetal Pericardial Tumours: Survival following in utero Shunting, and Literature Review

Cited by 27 publications

References 77 publications

Fetal Intrapericardial Teratomas: An Update

Fetal Intrapericardial Teratomas: An Update

Successful intrauterine treatment of nonimmune hydrops fetalis due to pericardial tumor

Pericardio-Amniotic Shunting for Incomplete Pentalogy of Cantrell

Contact Info

Product

Resources

About