2022
DOI: 10.1001/jamanetworkopen.2022.25614
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Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents With Tourette Syndrome

Abstract: IMPORTANCEThe availability of behavior therapy for individuals with Tourette syndrome (TS) and chronic tic disorder (CTD) is limited. OBJECTIVE To determine the efficacy and cost-effectiveness of internet-delivered exposure and response prevention (ERP) for children and adolescents with TS or CTD. DESIGN, SETTING, AND PARTICIPANTS This single-masked, parallel group, superiority randomized clinical trial with nationwide recruitment was conducted at a research clinic in Stockholm, Sweden.

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Cited by 14 publications
(22 citation statements)
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“…In ERP, patients are trained to suppress any or all tics as they are exposed to greater and greater stimuli (whether it be premonitory urges or environmental factors that elicit tics) for long periods of time [ 44 ]. The most recent ERP vs. psychoeducation RCT had 221 participants between the ages of 9–17 years old [ 45 ]. The treatment response rates were significantly higher in the ERP arm than the psychoeducation arm (47% vs. 29%; p = 0.05) [ 45 ].…”
Section: Epidemiologymentioning
confidence: 99%
See 1 more Smart Citation
“…In ERP, patients are trained to suppress any or all tics as they are exposed to greater and greater stimuli (whether it be premonitory urges or environmental factors that elicit tics) for long periods of time [ 44 ]. The most recent ERP vs. psychoeducation RCT had 221 participants between the ages of 9–17 years old [ 45 ]. The treatment response rates were significantly higher in the ERP arm than the psychoeducation arm (47% vs. 29%; p = 0.05) [ 45 ].…”
Section: Epidemiologymentioning
confidence: 99%
“…The most recent ERP vs. psychoeducation RCT had 221 participants between the ages of 9–17 years old [ 45 ]. The treatment response rates were significantly higher in the ERP arm than the psychoeducation arm (47% vs. 29%; p = 0.05) [ 45 ]. A unique aspect to this study was that it was all done through internet visits and still showed significant improvement in treatment response with ERP.…”
Section: Epidemiologymentioning
confidence: 99%
“…In addition, the results indicated that the internet delivered version had equal effects compared to the face-to-face version 35 . A Swedish RCT published in 2022 compared therapist-supported internet delivered ERP with therapistsupported internet delivered psychoeducation and found that both were associated with reduction in tic severity, but response rates and satisfaction were significantly higher in the ERP group 36 .…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…education for tics 21,25 . In guidelines from The American Academy of neurology 29 , insufficient evidence was found to recommend ERP as first-line treatment, since only one study with very low confidence in evidence has compared the effect of HRT vs. ERP 28 .…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…BT is traditionally offered as face-to-face with a clinician in a hospital environment, but during recent years more novel treatment delivery modalities have been tested, including web-based videoconferencing and online approaches [21][22][23][24][25] .…”
Section: Accepted Manuscriptmentioning
confidence: 99%