2019
DOI: 10.1007/s00105-019-04475-4
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Therapie des Handekzems

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Cited by 17 publications
(31 citation statements)
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References 31 publications
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“…Coal tar (Pix lithanthracis) with its additional antiproliferative and epidermal differentiation-inducing properties [140] is one of the oldest dermatological preparations and sometimes still used as therapy of hand eczemas, although without evidence of efficacy [2,4,92,93,106,136]. In general, its relevance in clinical dermatology is rapidly declining.…”
Section: Coal Tarmentioning
confidence: 99%
“…Coal tar (Pix lithanthracis) with its additional antiproliferative and epidermal differentiation-inducing properties [140] is one of the oldest dermatological preparations and sometimes still used as therapy of hand eczemas, although without evidence of efficacy [2,4,92,93,106,136]. In general, its relevance in clinical dermatology is rapidly declining.…”
Section: Coal Tarmentioning
confidence: 99%
“…Zahlreiche Behandlungsmöglichkeiten stehen für beruflich bedingte Handekzeme zur Verfügung. Welches Therapieverfahren letztlich gewählt wird, hängt vom Schweregrad des Handekzems, dem klinischen Typ sowie der Ursache ab [18]. Für die akute Therapie des Ekzems ist eine differenzierte Lokaltherapie erforderlich [1].…”
Section: Das Beruflich Verursachte Handekzemunclassified
“…Bezüglich des Managements von Handekzemen wird ein Stufenschema empfohlen, wobei die Therapie je nach Morphologie und Schweregrad des Handekzems stadienabhängig erfolgt. Die Therapie beinhaltet eine konsequente Basispflege (zum Beispiel mit Urea, Milchsäurederivaten, Glycin), Glukokortikosteroid-haltige Externa (Wirkstärke I-IV), topische Calcineurininhibitoren (Tacrolimus, Pimecrolimus), Ultraviolett-Phototherapie (zumeist Creme-PUVA-Therapie) sowie andere physikalische Therapien (zum Beispiel Leitungswasseriontophorese) und bei schwersten Handekzemen eine zusätzliche Systemtherapie (zum Beispiel orale Glukokortikosteroide, Alitretinoin, Ciclosporin, oder Azathioprin beziehungsweise Methotrexat als Off-Label-Anwendung) [18]. Lässt sich eine irritative oder kontaktallergische Genese ausmachen, ist es langfristig die oberste Priorität, eine Exposition gegenüber der auslösenden Noxe/des Allergens zu vermeiden oder zu verringern [19].…”
Section: Das Beruflich Verursachte Handekzemunclassified
“…Numerous treatment options are available for occupational hand eczema. Which treatment method is ultimately chosen depends on the severity of the hand eczema, the clinical type, and the cause [18]. For acute eczema therapy, a differentiated local therapy is required [1].…”
Section: Occupational Hand Eczemamentioning
confidence: 99%
“…Regarding the management of hand eczema, a staged regimen is recommended, with therapy depending on the morphology and severity of hand eczema. Therapy includes consistent basic care (for example, with urea, lactic acid derivatives, glycine), glucocorticosteroid-containing topicals (potency I-IV), topical calcineurin inhibitors (tacrolimus, pimecrolimus), ultraviolet phototherapy (mostly cream-PUVA therapy) and other physical therapies (for example, tap water iontophoresis) and, in the case of severe hand eczema, additional systemic therapy (for example, oral glucocorticosteroids, alitretinoin, ciclosporin, or azathioprine or methotrexate as an off-label application) [18]. The highest priority over the long term, upon identification of an irritant or origin for the contact allergy, is to avoid or reduce exposure to the causative agent/allergen [19].…”
Section: Occupational Hand Eczemamentioning
confidence: 99%