Therapie der obstruktiven Schlafapnoe mittels AlaxoStent©

Freuschle, A.; Heiser, Clemens; Maurer, Joachim T.; Hörmann, K.; Stuck, Boris A.

doi:10.1007/s11818-013-0614-0

Cited by 6 publications

(4 citation statements)

References 18 publications

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“…19 A rather high difference in treatment acceptance rates is found among these studies, ranging from very good to a 100% dropout rate after 2 weeks. 9,10,20…”

Section: Discussionmentioning

confidence: 99%

“…Different kinds of nasopharyngeal stents can be used for treatment of snoring and OSA, including conventional tubes used in rescue medicine, 6,8,10,17 the AlaxoStent 3,9,11 or the Na stent. 4 Few studies to date have examined the treatment acceptance of nasopharyngeal tubes over an elongated period of time.…”

Section: Discussionmentioning

confidence: 99%

“…19 A rather high difference in treatment acceptance rates is found among these studies, ranging from very good to a 100% dropout rate after 2 weeks. 9,10,20 In our study, the Na stent was mainly used for diagnostic purposes both in a split-night examination with the WatchPAT and during DISE. Overall, the Na stent was poorly tolerated, and 30% of patients complained of significant adverse effects.…”

Section: Discussionmentioning

confidence: 99%

“…8 Conventional stents, as well as the AlaxoStent, seem to be less readily tolerated by patients. 9,10 Yenigun et al. 11 reported the successful use of a similar nitinol-based, self-expanding nasopharyngeal stent in five patients.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of a nasopharyngeal stent in patients with obstructive sleep-related breathing disorders

2022

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Objective This study was performed to evaluate the therapeutic effect and diagnostic value of a novel nasopharyngeal stent (Naśtent; Corinium Medical Equipment Ltd., Cirencester, UK). The Naśtent is designed to stent palatal collapse in patients with sleep-related breathing disorders. Methods The study was conducted from 2018 to 2019. Patients who did not qualify for continuous positive airway pressure therapy underwent split-night examination with an inserted Naśtent for the first half of the night. The next morning, drug-induced sleep endoscopy (DISE) was performed. Results Of the 122 enrolled patients, 21 were excluded because of Naśtent intolerance (n = 14) or technically invalid examinations (n = 7). Among the remaining 101 patients, in correlation with DISE, the apnea–hypopnea index was significantly reduced in patients with palatal obstructions, mainly in those with anteroposterior collapse patterns. The Naśtent did not influence retrolingual or multilevel obstructions. Using a 40% reduction of the apnea–hypopnea index by the Naśtent as a cut-off value, 85.7% of soft palate obstructions were detected compared with DISE. Conclusions The Naśtent is a viable tool to reduce palatal obstructions, although it is not readily tolerated. It may also be helpful for diagnosis of sleep-related breathing disorders when DISE is unavailable.

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“…19 A rather high difference in treatment acceptance rates is found among these studies, ranging from very good to a 100% dropout rate after 2 weeks. 9,10,20…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of a nasopharyngeal stent in patients with obstructive sleep-related breathing disorders

2022

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Konservative Therapie der obstruktiven Schlafapnoe mit Nicht-PAP-Verfahren

Maurer

Leitzbach

2020

HNO

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A novel nasopharyngeal stent for the treatment of obstructive sleep apnea: a case series of nasopharyngeal stenting versus continuous positive airway pressure

Traxdorf

Hartl²,

Angerer

et al. 2015

Eur Arch Otorhinolaryngol

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The objective of the study was to investigate the first-night treatment success of a nasopharyngeal stent compared to standard nCPAP-titration. This is a case series and a single-center study. Eight participants (n = 8) were selected with untreated obstructive sleep apnea with a prestudy AHI ≥ 10. A newly developed nasopharyngeal stent was tested individually versus standard nCPAP-titration. Cardiorespiratory polysomnography was performed on two consecutive nights (random order: stent, nCPAP). The AHI, the number of obstructive apneas and hypopneas, the mean oxygen saturation, and the minimum oxygen saturation were compared before and after using the nasopharyngeal stent or standard nCPAP. The AHI value before treatment (AHIpre) was 31.1 ± 12.0 (mean ± standard deviation). After inserting the AlaxoStent, the mean AHIstent was 19 ± 12.0 compared to mean AHInCPAP 8.2 ± 11.9 with standard nCPAP-titration. Both nasopharyngeal stenting and nCPAP-titration could reduce the mean number of obstructive apneas by >94 %. Compared to responder rates of classic surgical interventions like uvulopalatopharyngoplasty or multi-level surgery, the nasopharyngeal stent seems to give a comparable responder rate of 50 %. There were no complications associated with the use of the stent and it was well tolerated by all subjects. Nasopharyngeal stenting widens the range of non-invasive mechanical treatment and seems to be an effective mechanical therapeutic alternative to surgery in nCPAP non-compliant patients with OSA. Careful selection of the patient population is a prerequisite of treatment and therefore it should be reserved for individual cases only.

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Therapie der obstruktiven Schlafapnoe mittels AlaxoStent©

Cited by 6 publications

References 18 publications

Evaluation of a nasopharyngeal stent in patients with obstructive sleep-related breathing disorders

Evaluation of a nasopharyngeal stent in patients with obstructive sleep-related breathing disorders

Konservative Therapie der obstruktiven Schlafapnoe mit Nicht-PAP-Verfahren

A novel nasopharyngeal stent for the treatment of obstructive sleep apnea: a case series of nasopharyngeal stenting versus continuous positive airway pressure

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