Therapie der akuten unkomplizierten Harnweginfektion

Wagenlehner, Florian M. E.; Hoyme, U. B.; Naber, Kurt G.

doi:10.1007/s00120-006-1022-x

Cited by 5 publications

(3 citation statements)

References 57 publications

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“…This may reflect a typical management strategy for uncomplicated UTI in outpatient care, with the goal of minimizing inconvenience to the patient, independently of conformity to the guidelines (19,20). Most of the…”

Section: Discussionmentioning

confidence: 99%

A Survey of Outpatient Antibiotic Prescribing for Cystitis

Velasco

Noll²,

Espelage³

et al. 2012

Deutsches Ärzteblatt International

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Section: Discussionmentioning

confidence: 99%

A Survey of Outpatient Antibiotic Prescribing for Cystitis

Velasco

Noll²,

Espelage³

et al. 2012

Deutsches Ärzteblatt International

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“…Most resource-limited settings are also unlikely to have the information that they need to guide empiric antimicrobial therapy 11,12. Diagnosis and susceptibility profiles of urinary pathogens are hampered by numerous factors in populations such as displaced people living on the Thai–Burmese border.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic and Treatment Difficulties of Pyelonephritis in Pregnancy in Resource-Limited Settings

McGready¹,

Wuthiekanun²,

Ashley³

et al. 2010

The American Society of Tropical Medicine and Hygiene

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Limited microbiology services impede adequate diagnosis and treatment of common infections such as pyelonephritis in resource-limited settings. Febrile pregnant women attending antenatal clinics at Shoklo Malaria Research Unit were offered urine dipstick, sediment microscopy, urine culture, and a 5-mL blood culture. The incidence of pyelonephritis was 11/1,000 deliveries (N = 53 in 4,819 pregnancies) between January 7, 2004 and May 17, 2006. Pyelonephritis accounted for 20.2% (41/203) of fever cases in pregnancy. Escherichia coli was the most commonly isolated pathogen: 87.5% (28/32) of organisms cultured. Susceptibility of E. coli to ampicillin (14%), cotrimoxazole (21%), and amoxicillin-clavulanic acid (48%) was very low. E. coli was susceptible to ceftriaxone and ciprofloxacin. The rate of extended spectrum β-lactamase (4.2%; 95% confidence interval = 0.7–19.5) was low. The rate and causes of pyelonephritis in pregnant refugee and migrant women were comparable with those described in developed countries. Diagnostic innovation in microbiology that permits affordable access is a high priority for resource-poor settings.

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“…16 The most common antibiotics being used-fluoroquinolones (FQs), 49% of all antibiotic prescription. 17,18 Our study assessed treatment efficacy with the clinical response because a significant percentage of patients had negative baseline cultures. The combined clinical and microbiological response would have excluded many patients from the sample.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Five Days Nitrofurantoin Therapy versus Fosfomycin Stat Dose in Clinical Resolution of Uncomplicated Urinary Tract Infections

Tahir

Khan²,

Khan³

et al. 2023

PAFMJ

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Objective: To compare the efficacy of 5-days Nitrofurantoin therapy versus Fosfomycin stat dose in clinical resolution of uncomplicated urinary tract infections in females of reproductive age group. Study Design: Comparative prospective study. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Apr 2019 to Mar 2020. Methodology: A total of 498 females of reproductive age (18 years to 40 years) with lower urinary tract infection symptoms(increased urinary hesitancy, frequent micturition, tenderness at suprapubic region) and positive urine dipstick test for nitrates/leukocyte esterase test were incorporated in the study. Patients were randomly assigned to Group-A and Group-B,comprising 249 patients. Group-A was given tablet Nitrofurantoin 100mg every six hourly. Group-B was given Fosfomycin 3gstat dose. Patients were advised to follow up on days 14 and 28 of treatment to observe the clinical resolution of urinary tractinfection symptoms and bacteriologic response. Results: Clinical resolution of urinary tract infection on the 28th day of treatment was attained in 172(69.1%) patients of the Nitrofurantoin-Group versus 140(56.2%) patients receiving Fosfomycin (p-value 0.003). Baseline urine cultures were positive in 286(57.4%) patients. Microbiologic resolution was achieved in 109 of 140(77.9%) and 100 of 146(68.4%) (p- value=0.026). Conclusion: Among the females of reproductive age, five days of Nitrofurantoin therapy is superior to stat dose Fosfomycin in the clinical and microbiologic resolution of uncomplicated urinary tract infections.

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Therapie der akuten unkomplizierten Harnweginfektion

Cited by 5 publications

References 57 publications

A Survey of Outpatient Antibiotic Prescribing for Cystitis

A Survey of Outpatient Antibiotic Prescribing for Cystitis

Diagnostic and Treatment Difficulties of Pyelonephritis in Pregnancy in Resource-Limited Settings

Efficacy of Five Days Nitrofurantoin Therapy versus Fosfomycin Stat Dose in Clinical Resolution of Uncomplicated Urinary Tract Infections

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