“… 4 , 5 When medical approaches fail, surgical procedures, including ventilation tube insertion, laser tuboplasty, and microdebrider tuboplasty, are usually required. 6 , 7 , 8 , 9 However, the efficacy of these surgical approaches remains uncertain owing to inconsistent diagnostic criteria in previous clinical studies and limited clinical experience. Moreover, surgical treatment may cause surgery-related complications such as purulent infection of the middle ear, airway obstruction, airway prolapse, and permanent tympanic membrane perforation.…”