Therapeutic use of mistletoe for CD30+ cutaneous lymphoproliferative disorder/lymphomatoid papulosis

Nodal Anaplastic Large-Cell Lymphoma ALK-1− with CD30+ Cutaneous Lymphoproliferation Treated with Mistletoe: Spontaneous Remission or Treatment Response?

“…Interestingly, Nijsten et al reported that 15 out of 35 patients never reached complete remission under diff erent therapies and 3 developed a second lymphoid neoplasia and that in 2 treated patients LyP recurred after discontinuing chemotherapy [ 9 ] . Similar observations were noted in our published case [ 10 ] . 3 weeks after discontinuing MT, relapse of LyP occurred.…”

“…malignant cells [ 3 , 6 ] . We previously published a paediatric casereport with LyP and ALCL which was successfully treated with chemotherapy and MT [ 10 ] . The objective of this case report is to discuss not only whether the complete remission of a cutaneous CD30+ lymphoproliferative disorder observed under MT-treatment was spontaneous remission or therapeutic response, but whether lymph node involvement in CD30-positive cutaneous lymphoproliferation indicates systematic ALK-1− ALCL.…”

Intralesional agents in the management of cutaneous malignancy: A review

“…57 He was first treated with combination chemotherapy and his lesions regressed, but 2 months after cessation of therapy the lesion on the arm returned. Biweekly intralesional injections of more than 20 mg of mistletoe extract were commenced.…”

Anthroposophic Supportive Treatment in Children With Medulloblastoma Receiving First-line Therapy

“…The only data available for pediatric oncology are individual case reports. 7,8 A theoretical risk of increased intracranial pressure and enhanced growth of tumors or leukemic cells in association with the administration of mistletoe extracts in cancers of the brain has repeatedly been discussed in the literature on the basis of some methodological lacking in vivo data. [9][10][11] However, no clinical evidence of this exists.…”