Therapeutic Results of Computed-Tomography-Guided Transcatheter Arterial Chemoembolization for Local Recurrence of Hepatocellular Carcinoma After Initial Transcatheter Arterial Chemoembolization: The Results of 85 Recurrent Tumors in 35 Patients

Abstract

The aim of this study was to retrospectively evaluate the long-term results of transcatheter arterial chemoembolization (TACE) for the treatment of local recurrence of hepatocellular carcinoma (HCC) after the first TACE. Between September 1992 and October 2004, 85 recurrent HCC nodules of 35 patients were treated by TACE. During the median follow-up period of 15.5 months (range 1.9-58.6 months), 58 of the 85 treated tumors developed local recurrence again after the second TACE. The overall 6-, 12-, and 36-month recurrence-free rates of these tumors after the second TACE were 47.0%, 36.2%, and 25.8%, respectively. Local recurrence of HCC after the first TACE was treated by a second TACE with equivalent efficacy as that of the initial TACE, if segmental chemoembolization was achieved. We regard TACE as the treatment of choice for the management of local recurrence of HCC.

Recurrences of hepatocellular carcinoma following complete remission by transarterial chemoembolization or radiofrequency therapy: Focused on the recurrence patterns

“…In the current study, the 1‐, 3‐ and 5‐year recurrence rates of HCC following CR by TACE were 21%, 68% and 81%, respectively, and the rates in the RFA group were 26%, 56% and 74%, respectively. Also, in the previous studies, the cumulative 1‐, 2‐ and 3‐year recurrence rates have been reported to be 23–32%, 55–63% and 67–84%, respectively, in HCC patients with CR by TACE, and the cumulative recurrence rates following CR by RFA were 35–42%, 46–72% and 63–80%, respectively.…”

Clinical usefulness of the triaxial system in super-selective transcatheter arterial chemoembolization for hepatocellular carcinoma

“…However, it was mostly used at a sub-subsegmental artery or a more distal artery. Third, the local tumor control rate was lower than that in previous reports (5,11,12). We think our TACE may be incomplete even though we could insert a microcatheter into a distal position.…”

In Vivo Evaluation of Feeding Arteries of Tumors in Dorsal Sector of the Liver

“…The identification of the dorsal sector of the liver and its detailed anatomy is of primary importance for surgical practice. Segmental transcatheter arterial chemoembolization (TACE) possesses markedly stronger anticancerous effect but much less damage to liver function; hence, its long-term effectiveness excels the conventional TACE in liver cancers treatment ( 5 - 7 ). A sufficient segmental TACE of the tumor in the dorsal sector depends on the identification of feeding arteries to the segment; however, the origin of hepatic arterial blood supplying to the dorsal sector is intricate and needs further research.…”