Therapeutic Potentials of Neem Against Malaria Parasite: A Review

Abstract

Malaria presents a significant public health threat, affecting both developed and developing nations. The rise of drug resistance in regions with high malaria prevalence has posed challenges in effectively managing the disease. Azadirachta Indica, commonly known as the neem plant, has long been recognized as a medicinal plant in Asia and Africa, with historical usage in treating malaria parasites. The neem plant contains various bioactive compounds, making it a popular ingredient in traditional remedies. This study aimed to assess the effectiveness of neem leaf and seed extracts in combating malaria parasites. The information used in this review was obtained from previously published studies sourced from various journals. The findings suggest that neem (Azadirachta indica) seeds or leaves show promise as a potential treatment for inhibiting the malaria parasite. However, further research is required to ascertain the antimalarial potency of the neem plant before confidently recommending it as a treatment for malaria parasites.