“…MLR refers to the oral supplementation with natural cell membrane glycerophospholipids and kaempferol (3,4′,5,7-tetrahydroxyflavone), a natural flavonoid found in tea, broccoli, cabbage, kale, beans, endive, leek, tomato, strawberries, and grapes [ 161 ]. Kaempferol is a glycogen synthase kinase-3β (GSK-3β) inhibitor which prevents sleep deprivation-induced cognitive decline [ 162 , 163 ]. Like lithium and several antipsychotic drugs, kaempferol blocks GSK-3β, an enzyme previously implicated in SCZ and circadian rhythm disorders, suggesting that this natural compound may exert antipsychotic properties without the adverse effects of conventional therapeutics [ 164 , 165 , 166 , 167 ].…”