Abstract:Phytonutrients get attention now days due to their wide application and their tendency to improve the productive and reproductive performance in humans. Hydrolysable tannin (HT) is one of these bionutrients. The present study was aimed to investigate the therapeutic effect of HT on the induced polycystic ovarian syndrome (PCOS) in rats. Forty-five adult female rats with 4 to 5 days regular estrous cycle were selected. The PCOS was induced by a single intramuscular injection of Estradiol Valerate 4 mg/rat/kg. T… Show more
“…4 In PCOS patients, the increased levels of serum testosterone were due to the high levels of serum cholesterol as previously reported. 34 However, the intake of the fiber diet reduced the level of cholesterol, which further helped to decrease the synthesis of steroid hormones like testosterone in PCOS females and its conversion into estrogen 35 which was also another finding of the present study. A high decrease in the acne percentage was observed in the PC group and a mild effect was observed in alginate-treated groups SA3 and SA6, respectively (Table 3).…”
Section: Discussionsupporting
confidence: 74%
“…4 In PCOS patients, the increased levels of serum testosterone were due to the high levels of serum cholesterol as previously reported. 34 However,…”
Dietary fibers get attention these days due to their tendency to improve the productive performance in human beings. Sodium alginate (SA) is one of the natural dietary fibers. The present...
“…4 In PCOS patients, the increased levels of serum testosterone were due to the high levels of serum cholesterol as previously reported. 34 However, the intake of the fiber diet reduced the level of cholesterol, which further helped to decrease the synthesis of steroid hormones like testosterone in PCOS females and its conversion into estrogen 35 which was also another finding of the present study. A high decrease in the acne percentage was observed in the PC group and a mild effect was observed in alginate-treated groups SA3 and SA6, respectively (Table 3).…”
Section: Discussionsupporting
confidence: 74%
“…4 In PCOS patients, the increased levels of serum testosterone were due to the high levels of serum cholesterol as previously reported. 34 However,…”
Dietary fibers get attention these days due to their tendency to improve the productive performance in human beings. Sodium alginate (SA) is one of the natural dietary fibers. The present...
“…If HDG pathology was abnormal, LDG and MDG pathology studies were performed. The sectioned tissue was soaked and fixed in 10% formaldehyde buffer, cut into thin sections, dehydrated, and embedded in paraffin, stained with standard hematoxylin and eosin, and examined under light microscope (Manzoor et al, 2022).…”
Despite the use of Maillard reaction products (MRPs) as food flavoring and coloring agents, they are also known to constitute acrylamide, heterocyclic amines, advanced glycosylation end products, and precursors of low molecular weight compounds. The very little is known about the toxicology of peony seed meal-derived MRPs. In this study, sub-chronic toxicity of peony seed meal derived MRPs was evaluated in Sprage-Dawley (SD) rats. Results showed that the body weight, hematology and serum biochemistry, organ coefficient and histopathology of SD rats with daily intake of peony seed meal-derived MRPs lower than 0.45 g/kg were not affected. After feeding with peony seed meal-derived MRPs for 13-weeks, there were no significant toxic effect on either male or female rats. This study provides a theoretical basis for the safety of MRPs derived from the reactants of enzymatic hydrolysis of peony seed meal.
“…The former refers to the condensation products of hydroxyflavanes, which are interconnected by C-C bonds and are not easy to decompose in water, while the latter is an ester whose ester bond is easy to hydrolyze under the action of alkali, enzyme or acid. Tannin can react with enzymes and metal ions, and is able to combine with proteins, generating pharmacological effects on convergence, anti-inflammation, sedation, anticoagulation, anti-oxidation, and anti-tumor (Manzoor et al, 2022;Ha et al, 2022;Das et al, 2020;Fraga-Corral et al, 2020). What's more, its extensive application can be observed in other various aspects including tanning agents' adhesives, additives, preservatives, and water treatment (Das et al, 2020;Guo et al, 2020).…”
The woody oil industry generates a large amount of seed shell waste during its production. Therefore, this paper employs a central composite design (CCD) methodology to optimize the ultrasonic-assisted extraction process, thus utilizing the byproduct. The infrared spectrum and thermogravimetric analysis is adopted to explore the chemical structure and thermal stability of tannin. Besides, the tannin resin (TF) is prepared to elaborate its adsorbing performance for dyes in water. The results verify the role of ultrasonic-assisted extraction method in increasing yield rate. The optimal conditions are as follows: 60% ethanol as extraction solvent, the solid-liquid ratio of 1:25 (g/mL), ultrasonic power of 160 W, and extracted at 80 o C for 60min. The yield rate of tannin under such conditions stands at 32.04% (w/w). Temperature is vital for the extraction rate. Acer truncatum tannin as a condensed tannin, performs favorable thermal stability, and TF effectively absorbs cationic dye in water. The maximum adsorption capacity of methylene blue peaks at 176.13 mg/g. Acer truncatum shell serves as a resource of condensed tannin, and Acer truncatum tannin resin can be potentially developed into a new biomass adsorbent.
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