Abstract:Arthritis is a common degenerative disease of joints, which has become a public health problem affecting human health, but its pathogenesis is complex and cannot be eradicated. Coptis chinensis (CC) has a variety of active ingredients, is a natural antibacterial and anti-inflammatory drug. In which, berberine is its main effective ingredient, and has good therapeutic effects on rheumatoid arthritis (RA), osteoarthritis (OA), gouty arthritis (GA). RA, OA and GA are the three most common types of arthritis, but … Show more
A new nanocomplex T-BBR was synthesized by carrying BBR with tFNAs. Compared with BBR, T-BBR showed better osteogenic and anti-osteoporosis abilities in both in vivo and in vitro experiments through the Wnt/β-catenin signaling pathway.
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