Therapeutic pathology: time to move beyond diagnostics

Smith, Brian R.

doi:10.1016/j.humpath.2008.04.004

Cited by 8 publications

(9 citation statements)

References 13 publications

(12 reference statements)

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“…The ACLPS Committee recognizes the value of creative approaches but agreed that it was nevertheless worthwhile to make general recommendations on goals and objectives in laboratory medicine that might be effectively incorporated into a classic structure or used in planning new pathways of education. Because the field is not organ-or system-based but rather considers all diagnostics and therapeutics whose common theme is the use of the clinical laboratory, 42,43 it represents more of a challenge and also more of an opportunity for creativity. Just as pharmacology can be incorporated successfully throughout an integrated curriculum, in the "preclinical" and the "clinical" years, so it is with laboratory medicine.…”

Section: General Considerationsmentioning

confidence: 99%

Educating Medical Students in Laboratory Medicine

et al. 2010

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As the 100th anniversary of the Flexner report nears, medical student education is being reviewed at many levels. One area of concern, expressed in recent reports from some national health care organizations, is the adequacy of training in the discipline of laboratory medicine (also termed clinical pathology). The Academy of Clinical Laboratory Physicians and Scientists appointed an ad hoc committee to review this topic and to develop a suggested curriculum, which was subsequently forwarded to the entire membership for review. The proposed medical student laboratory medicine curriculum defines goals and objectives for training, provides guidelines for instructional methods, and gives examples of how outcomes can be assessed. This curriculum is presented as a potentially helpful outline for use by medical school faculty and curriculum committees.

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Section: General Considerationsmentioning

confidence: 99%

Educating Medical Students in Laboratory Medicine

et al. 2010

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“…In the United States of America (US), we feel the convergence of two historic trends will substantially accelerate advances in what BR Smith calls "therapeutic pathology." [1]. In the US, the proportion of non-US citizen international medical graduates (non-US IMGs) is increasing at the same time cellular therapeutics is expanding [1,2].…”

mentioning

confidence: 99%

“…[1]. In the US, the proportion of non-US citizen international medical graduates (non-US IMGs) is increasing at the same time cellular therapeutics is expanding [1,2]. Even separately, these trends would significantly impact patient care.…”

mentioning

confidence: 99%

Pathology's historic 2019 incoming residents: Why “the internationalization of pathology” may markedly advance transfusion medicine and cellular therapeutics

Jajosky

Jajosky³

2020

Transfusion and Apheresis Science

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This study had two objectives: (1) to determine if, in the United States of America (US), the proportion of non-US citizen international medical graduates (non-US IMGs) entering pathology residencies had increased (again) in 2019 and (2) to assess how this multi-year trend might impact transfusion medicine in the US. Methods: The most recent (2019) "National Resident Matching Program" (NRMP) data were analyzed. To assess potential future impact, using controversies related to Plasmodium falciparum (Pf) malaria, conflicting US and non-US perspectives were reviewed. Differences between published US and non-US views were identified regarding, for example, the value of Pf-resistant ("variant") red blood cells (RBCs) and exchange transfusions. Results: Year 2019 is the first year non-US IMGs were the largest group to fill residency-training positions for a major US specialty via the "Main Residency Match." Also notable, US and non-US views were found to differ markedly regarding (1) the value and safety of Pf-resistant RBC variants and exchange transfusions, and (2) the threat of drug-resistant Pf-malaria parasites. Non-US clinicians and researchers seem more concerned about Pfmalaria, and their interest in cellular therapies seems greater and more optimistic. Conclusions: In 2019, the historically high proportion of non-US IMGs among incoming pathology residents dramatically highlights the steady demographic shift that began years ago: "the internationalization of pathology" in the US. Fortunately, a review of publications related to exchange transfusion, Pf-malaria, and variant RBCs suggests non-US IMGs may markedly promote and advance cell therapies such as therapeutically-rational exchange (T-REX) of disease-resistant RBCs.

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“…Practitioners in transfusion medicine have long been involved in consultations emphasizing clinical issues such as alloantibody reporting, blood product utilization, and transfusion reaction evaluation . Based on these and other opportunities for clinical consultation, the modern day blood banker remains at the forefront of “therapeutic pathology,” that is, the application of laboratory‐based medical knowledge and expertise to both diagnostic and therapeutic interventions . In addition to consultative practice in the areas noted, there are also previously described examples of blood bankers providing expanded consultation at the interface of laboratory coagulation and transfusion.…”

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confidence: 99%

The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology

Tormey

Smith

2012

Transfusion

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Practitioners in transfusion medicine, long involved in consultations emphasizing clinical issues such as alloantibody reporting and transfusion reaction evaluation, have more recently been engaged as experts and consultants in hemostasis and coagulation. Given the growing complexity in laboratory coagulation testing and its interpretation, the shortage of specialists in this arena, and the increasing costs associated with patient management, we believe that there are vital clinical roles in hemostasis that can be readily fulfilled by transfusion medicine practitioners. The aim of this article is to briefly outline three possible models by which transfusion medicine practitioners can begin to integrate coagulation consultation into their regular clinical practice. Moreover, we discuss a novel curriculum that we are developing at our institution to more fully train transfusion medicine fellows in the fields of hemostasis and thrombosis.

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Therapeutic pathology: time to move beyond diagnostics

Cited by 8 publications

References 13 publications

Educating Medical Students in Laboratory Medicine

Educating Medical Students in Laboratory Medicine

Pathology's historic 2019 incoming residents: Why “the internationalization of pathology” may markedly advance transfusion medicine and cellular therapeutics

The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology

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