Therapeutic options in SARS-CoV-2 infection

Mitea, Gabriela; Bucur, Maria; Dumitru, Irina-Magdalena; Rugină, Sorin; Bucur, Laura

doi:10.26416/farm.195.4.2020.3729

Cited by 1 publication

(1 citation statement)

References 17 publications

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“…Non-COVID-19 patients should also be isolated so as to minimize the risk of contamination. The pandemic caused by the new coronavirus is of great importance for public health, and its evolution is a cause for concern (Mitea et al, 2020).…”

Section: Anticoagulant Drugsmentioning

confidence: 99%

THERAPEUTIC MANAGEMENT OF PATIENTS INFECTED WITH SARS-CoV-2 VIRUS - A REVIEW

Blebea

Mitea

2021

PMP

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INTRODUCTION: Due to the rapid outbreak of the pandemic that causes SARS-CoV-2 infection and the increased rate of morbidity and mortality as a result of this new infection, the treatments pursued in therapy must have an increased potential to inhibit the replication of this virus. OBJECTIVES: The main objective of this article was to describe the most current drug therapies and their mechanisms of action used in the treatment of COVID-19. In this article, we have collected the latest information and multilingual international scientific discoveries about the treatment of COVID-19. RESULTS: Several compounds can be used to treat COVID-19 in order to reduce the duration of the disease and the rate of infection, to reduce the viral load, to prevent tissue damage, to stimulate the maturation of many cells, including immune cells in the human body and to reduce its severe symptoms. The most effective treatments were based on the antiviral drugs, antimalarial drugs, anti-inflammatory drugs, analgesics drugs, glycopeptide antibiotics, anticoagulants, vitamin C and vitamin D. The simplest and most direct approach to controlling SARS-CoV-2 outbreaks is the use of passive antibodies transferred from plasma to convalescent patients. Recently, studies have been completed for several vaccines that are approved against SARS-CoV-2. CONCLUSION: Scientists around the world are collaborating and innovating to make tests, treatments and vaccines available to the public that will save lives collectively and end this pandemic.

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Section: Anticoagulant Drugsmentioning

confidence: 99%