Therapeutic options for elderly patients with advanced non-small cell lung cancer

Avery, Eric; Kessinger, Anne; Ganti, Apar Kishor

doi:10.1016/j.ctrv.2008.10.008

Cited by 24 publications

(14 citation statements)

References 50 publications

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“…Prognostic factors, such as the Eastern Cooperative Oncology Group's (ECOG) performance status, which provide a useful guide in making treatment decisions for younger patients, are often insufficient to assess the overall status of elderly patients. 26,27 Factors that need to be evaluated in elderly patients include functional status, co-morbidity, and cognition. These factors can have a negative effect on the possible benefits of treatment, and they must be considered and corrected if possible.…”

Section: Discussionmentioning

confidence: 99%

Role of chemotherapy in the very elderly patients with metastatic pancreatic cancer — A Veterans Affairs Cancer Registry analysis

Aldoss

Tashi

Gonsalves

et al. 2011

Journal of Geriatric Oncology

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Section: Discussionmentioning

confidence: 99%

Role of chemotherapy in the very elderly patients with metastatic pancreatic cancer — A Veterans Affairs Cancer Registry analysis

Aldoss

Tashi

Gonsalves

et al. 2011

Journal of Geriatric Oncology

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“…A small number of trials have examined how elderly patients tolerate chemotherapy. The different outcome has been explained as diversity in comorbidity [16,20]. Carefully selected patients older than 70 years tolerate doublet chemotherapy and seem to have an improvement in overall survival [21].…”

Section: Discussionmentioning

confidence: 99%

Trends in lung cancer in elderly in Denmark, 1980–2012

et al. 2016

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Background Lung cancer is an increasing problem in the older patient population due to the improvement in life expectation of the Western population. In this study we examine trends in lung cancer incidence and mortality in Denmark from 1980 to 2012 with special focus on the elderly. Material and methods Lung cancer was defined as ICD-10 codes C33-34. Data derived from the NORDCAN database with comparable data on cancer incidence, mortality, prevalence, and relative survival in the Nordic countries, where the Danish data were delivered from the Danish Cancer Registry and the Danish Cause of Death Registry with follow-up for death or emigration until the end of 2013. Results In 2012, about 50% of lung cancers were diagnosed among persons aged 70 years or more. For men and women older than 75 years the incidence rates have been increasing and for those aged 80-84 years, the rates have doubled since 1980. Due to the poor survival, similar trends were seen in mortality rates. Over the period, the one-year relative survival rates almost doubled in patients aged 70 years or more, but still only 25% of the patients aged 80-89 years survived their lung cancer for one year. Conclusion The incidence of lung cancer is closely linked to the pattern of tobacco smoking with the differences between gender and age groups reflecting smoking behavior in birth cohorts. Elderly patients with lung cancer are a heterogeneous group in whom treatment should be offered according to comorbidity and a geriatric assessment.

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“…Non-small cell lung cancer (NSCLC) has become the most common cause of cancer-related deaths worldwide and the median age of patients at the time of diagnosis is > 70 years [1,2]. As the population continues to age, the number of elderly patients with lung cancer is expected to further increase in the near future.…”

Section: Introductionmentioning

confidence: 99%

A nomogram to predict prognosis after surgery in early stage non-small cell lung cancer in elderly patients

Sun

Yang

et al. 2017

International Journal of Surgery

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Therapeutic options for elderly patients with advanced non-small cell lung cancer

Cited by 24 publications

References 50 publications

Role of chemotherapy in the very elderly patients with metastatic pancreatic cancer — A Veterans Affairs Cancer Registry analysis

Role of chemotherapy in the very elderly patients with metastatic pancreatic cancer — A Veterans Affairs Cancer Registry analysis

Trends in lung cancer in elderly in Denmark, 1980–2012

A nomogram to predict prognosis after surgery in early stage non-small cell lung cancer in elderly patients

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