1994
DOI: 10.1093/cvr/28.2.286
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Therapeutic modulation of ATP sensitive potassium channels in ischaemia

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“…[ 6 ] Furthermore, our results reveal one limitation of ABI is the existence of “false negatives” in the presence of partial arterial stenosis with calcified walls, thus portraying a normal ABI patient in the presence of CLI. Another clinically relevant phenomenon is that distal embolization can be induced following PTA treatment of stenosis [ 7 , 8 ] due to residual particles of the atheromatous plaque.…”
Section: Discussionmentioning
confidence: 99%
“…[ 6 ] Furthermore, our results reveal one limitation of ABI is the existence of “false negatives” in the presence of partial arterial stenosis with calcified walls, thus portraying a normal ABI patient in the presence of CLI. Another clinically relevant phenomenon is that distal embolization can be induced following PTA treatment of stenosis [ 7 , 8 ] due to residual particles of the atheromatous plaque.…”
Section: Discussionmentioning
confidence: 99%
“…A clinically relevant situation is that PTA can induce the formation of a "dust" of atheromatous plaque and distal embolization after treatment of stenosis. 9,10 This might explain the reduction of oxygen in some patients in whom an increase in the arterial diameter is not followed by a concomitant increase in TcPO 2 but, paradoxically, shows a decrease in the same. In our study, another 7.5% of the patients had a TcPO 2 lower than the initial PTA and were inconspicuous after Doppler imaging (ABI).…”
Section: Discussionmentioning
confidence: 99%