Therapeutic Hypothermia for Acute Myocardial Infarction and Cardiac Arrest

Schwartz, Bryan G.; Kloner, Robert A.; Jue, Thomas; Bui, Quang T.; Mayeda, Guy S.; Burstein, Steven; Hale, Sharon L.; Economides, Christina; French, William J.

doi:10.1016/j.amjcard.2012.03.048

Cited by 34 publications

(31 citation statements)

References 34 publications

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“…Previous studies suggested that target body temperature management or therapeutic hypothermia increases the chances of survival with a favorable neurologic outcome, and hypothermia may ameliorate myocardial damage in acute myocardial infarction. 36- 38 As the particularity of bath-related OHCAs would be higher body temperature immediately after cardiac arrests, it may cause a poorer prognosis. Other explanations would be that bathrelated OHCAs were less likely to be witnessed by bystanders (6.4% in home baths and 17.6% in public baths), as well as the fact that OHCAs with VF were very few (1.2% in home baths and 2.9% in public baths).…”

Section: Figurementioning

confidence: 99%

Characteristics and Outcomes of Bath-Related Out-of-Hospital Cardiac Arrest in Japan

Kiyohara

Nishiyama

Hayashida³

et al. 2016

Circ J

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Section: Figurementioning

confidence: 99%

Characteristics and Outcomes of Bath-Related Out-of-Hospital Cardiac Arrest in Japan

Kiyohara

Nishiyama

Hayashida³

et al. 2016

Circ J

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“…In more recent time hypothermia has been reintroduced to clinical practice as "therapeutic hypothermia" in the handling of cardiac victims after myocardial infarction [9]. Its use has signi icantly contributed to improve the outcome.…”

Section: Discussionmentioning

confidence: 99%

Brain changes in Hypothermia: Surface-versus Core-cooling in pigs

Morild¹

2017

J Forensic Sci Res

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The process of hypothermia in the clinical setting has been practiced for 50 years and is known for its neuroprotective properties. This paper describes histopathological changes either by an ice sludge mimicking accidental hypothermia (S-group n=7) or by endovascular core-cooling (C-group n=7). Focal infi ltrates of neutrophilic granulocytes were found in fi ve of seven brains in the S-group and in one of seven brains in the C-group. These granulocytes were found in the arachnoids, in vessels, in vessel walls, and in the cerebral cortex. Fungi, bacteria, lymphocytes or plasma were not found.This experimental study, mimicking accidental hypothermia, reported histopathologic features of aseptic infl ammation. To our knowledge, such fi ndings have not been described in hypothermic animals or humans before. We suggest that a local infl ammatory response may be triggered in such cases of hypothermia.

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“…Furthermore, cooling the body temperature also initiates compensatory mechanisms in the form of shivering, further delaying the cooling process, especially REviEW Ganjehei, Rashid, Payami & Saal future science group in conscious patients. At present, the feasible methods of inducing and maintaining hypothermia include surface cooling, endovascular cooling catheters, intravenous infusion of cold fluids and peritoneal lavage with cold solutions [44]. Two clinical trials are currently underway in order to evaluate therapeutic hypothermia as an adjunct to PCI in STEMI patients.…”

Section: Therapeutic Hypothermiamentioning

confidence: 98%

ST Elevation Myocardial Infarction: Recent Advances and Updates

et al. 2014

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ST elevation myocardial infarction (STEMI) remains a leading cause of morbidity, mortality and disability worldwide. Statistically, a trend towards improvements in morbidity and mortality has been consistent over the years, which is attributed primarily to the modification of risk factors, healthier lifestyles, treatment advances and better management of door-to-balloon times via STEMI systems. However, a major challenge in the coming years will be the baby boomers (born between the years 1946 and 1964) coming into old age. The first baby boomers turned 65 in year 2011. As the baby boomers age in the coming years, the incidence of coronary heart disease is likely to increase, and so there will be a greater need to have major advances in the management of coronary heart disease in order to deal with this additional incidence. The scope of this article is to review recent advances in the management of STEMI and to provide an updated overview.

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Therapeutic Hypothermia for Acute Myocardial Infarction and Cardiac Arrest

Cited by 34 publications

References 34 publications

Characteristics and Outcomes of Bath-Related Out-of-Hospital Cardiac Arrest in Japan

Characteristics and Outcomes of Bath-Related Out-of-Hospital Cardiac Arrest in Japan

Brain changes in Hypothermia: Surface-versus Core-cooling in pigs

ST Elevation Myocardial Infarction: Recent Advances and Updates

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