Therapeutic efficacy of transarterial chemo-embolization with a fine-powder formulation of cisplatin for hepatocellular carcinoma

Abstract

TACE using a suspension of DDPH in LPD may be a useful treatment for HCC.

Transarterial chemoembolization in hepatocellular carcinoma with portal vein tumor thrombosis: a systematic review and meta-analysis

“…All studies were from Asian countries, with eight from China, [10][11][12][13][14][15][16][17] one from Japan, 18 three from Korea, [19][20][21] and one from Taiwan. 22 Publication dates were all between 2009 and 2016.…”

“…1). Ten studies [10][11][12][13][14][15][16][17]19,21 provided patients classified as having MPV occlusion available for analysis (n = 806), and ten studies [10][11][12][13][14][16][17][18]21,22 provided PVB patients available for analysis (n = 995).…”

“…Selection criteria for patients eligible to receive TACE varied between studies (Supplemental Table 3), but TACE was typically only offered to Child-Pugh class A or B patients. [10][11][12][13][14][15][16][17]19 Several studies also excluded patients with distant metastasis 12,14,16,18,22 or PVT in the main portal vein. 18,22 TACE technique Details of the TACE procedure were similar for all studies.…”

Lipiodol retention pattern predicts transarterial chemoembolization therapeutic effect in hepatocellular carcinoma

“…(17) Transcatheter arterial chemoembolization combined with lipiodol as embolant has been reported to be one of the most effective palliative treatment for HCC. (11,12) The dose of lipiodol should be adequate to yield good therapeutic effect, but it must not be excessive, since the lipiodol may undergo reverse flow to the normal liver parenchyma, decreasing liver function and resulting in liver cirrhosis. There is no agreement yet in the literature on the volume of lipiodol to be used in TACE.…”

“…The cumulative survival rate of HCC patients receiving TACE therapy is 90.6% with a median survival time of 46.6 months. (12) Radiological investigations play an important role in establishing the diagnosis and treatment of HCC. Multiphasic CT scans and MRI are important imaging modalities in HCC diagnosis and follow-up, particularly to visualize contrast enhancement patterns.…”