Therapeutic efficacy of platelet-rich plasma injection compared to corticosteroid injection in plantar fasciitis: A systematic review and meta-analysis

Mohammed, Wafi; Farah, Salma; Nassiri, Mujtaba; McKenna, J

doi:10.1016/j.jor.2020.03.053

Cited by 9 publications

(10 citation statements)

References 55 publications

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“…Agree, n = 53; disagree, n = 0; abstain, n = 0. Agreement = 100% Four meta-analysis studies having compared US-guided PRP and corticosteroid support the use of PRP instead of corticosteroids, highlighting the favorable and long-lasting clinical outcomes in patients with chronic PF [10,[49][50][51].…”

Section: Level Of Evidence:mentioning

confidence: 98%

Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)—part VI, foot and ankle

et al. 2021

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Objectives Clarity regarding accuracy and effectiveness for interventional procedures around the foot and ankle is lacking. Consequently, a board of 53 members of the Ultrasound and Interventional Subcommittees of the European Society of Musculoskeletal Radiology (ESSR) reviewed the published literature to evaluate the evidence on image-guided musculoskeletal interventional procedures around this anatomical region. Methods We report the results of a Delphi-based consensus of 53 experts from the European Society of Musculoskeletal Radiology who reviewed the published literature for evidence on image-guided interventional procedures offered around foot and ankle in order to derive their clinical indications. Experts drafted a list of statements and graded them according to the Oxford Centre for evidence-based medicine levels of evidence. Consensus was considered strong when > 95% of experts agreed with the statement or broad when > 80% but < 95% agreed. The results of the Delphi-based consensus were used to write the paper that was shared with all panel members for final approval. Results A list of 16 evidence-based statements on clinical indications for image-guided musculoskeletal interventional procedures in the foot and ankle were drafted after a literature review. The highest level of evidence was reported for four statements, all receiving 100% agreement. Conclusion According to this consensus, image-guided interventions should not be considered a first-level approach for treating Achilles tendinopathy, while ultrasonography guidance is strongly recommended to improve the efficacy of interventional procedures for plantar fasciitis and Morton’s neuroma, particularly using platelet-rich plasma and corticosteroids, respectively. Key Points • The expert panel of the ESSR listed 16 evidence-based statements on clinical indications of image-guided musculoskeletal interventional procedures in the foot and ankle. • Strong consensus was obtained for all statements. • The highest level of evidence was reached by four statements concerning the effectiveness of US-guided injections of corticosteroid for Morton’s neuroma and PRP for plantar fasciitis.

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Section: Level Of Evidence:mentioning

confidence: 98%

Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)—part VI, foot and ankle

et al. 2021

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Section: Prp Vs Corticosteroidmentioning

confidence: 99%

“…The remaining reviews, all published in 2020, used different inclusion criteria and search periods which resulted in conflicting results [49][50][51][52][53][54]. Of these, four reviews combined RCTs with non-RCTs [49][50][51][52]. Huang et al included 10 studies, but in their analysis, they ended up pooling only eight RCTs and concluded that PRP provided long-term (≥6 months) improvement in AOFAS scores over corticosteroids, but no difference in pain VAS scores were observed between PRP and corticosteroids [49].…”

Section: Prp Vs Corticosteroidmentioning

confidence: 99%

“…Huang et al included 10 studies, but in their analysis, they ended up pooling only eight RCTs and concluded that PRP provided long-term (≥6 months) improvement in AOFAS scores over corticosteroids, but no difference in pain VAS scores were observed between PRP and corticosteroids [49]. Mohammed et al included 10 prospective studies and found that PRP showed greater VAS score reduction compared to corticosteroid at 3 and 6 months [50]. Alkhatib et al included 4 prospective cohort studies and 11 RCTs and concluded that PRP was associated with higher AOFAS score at 6 months and lower VAS scores at 6 and 12 months [52].…”

Section: Prp Vs Corticosteroidmentioning

confidence: 99%

“…The results were also different, as Hurley et al found that PRP offered benefits in terms of VAS score reduction at 1-1.5, 3, 6, and 12 months and AOFAS score improvement at 6 and 12 months over corticosteroid; [53] however, Tseng et al found no difference between autologous blood-derived products (e.g., PRP and whole blood) and corticosteroid as measured by VAS or AOFAS scores at all time points [54]. It is important to note that even though those authors who limited their analysis to PRP, heterogeneity in PRP such as different concentrations of platelets, leukocytes, growth factors as well as variation in centrifugation speed and time were seen across the studies they included [46,47,[49][50][51][52][53].…”

Section: Prp Vs Corticosteroidmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review of Systematic Reviews on the Epidemiology, Evaluation, and Treatment of Plantar Fasciitis

Rhim

Kwon

Park

et al. 2021

Life

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The number of systematic review and meta-analyses on plantar fasciitis is expanding. The purpose of this review was to provide a comprehensive summary of reviews on the topic pertaining to plantar fasciitis, identify any conflicting and inconsistent results, and propose future research direction. A qualitative review of all systematic reviews and meta-analyses related to plantar fasciitis up to February 2021 was performed using PubMed, Embase, Web of Science, and the Cochrane Database. A total of 1052 articles were initially identified and 96 met the inclusion criteria. Included articles were summarized and divided into the following topics: epidemiology, diagnosis, and treatment. While the majority of reviews had high level of heterogeneity and included a small number of studies, there was general consensus on certain topics, such as BMI as a risk factor for plantar fasciitis and extracorporeal shockwave therapy as an effective mode of therapy. A qualitative summary of systematic reviews and meta-analyses published on plantar fasciitis provides a single source of updated information for clinicians. Evidence on topics such as the epidemiology, exercise therapy, or cost-effectiveness of treatment options for plantar fasciitis are lacking and warrant future research.

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Platelet‐rich plasma injections as a treatment for Achilles tendinopathy and plantar fasciitis in athletes

Sneed

Wong

2023

PM&R

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Platelet‐rich plasma (PRP) injections represent a growing interest in the use of biologic therapies for treatment of musculoskeletal injuries. One possible application of PRP is in the management of overuse injuries commonly experienced by athletes. The aim of this review is to evaluate and summarize existing evidence regarding the efficacy of PRP in the treatment of Achilles tendinopathy and plantar fasciitis in athletes. Although many lower quality single‐armed studies have demonstrated clinical improvement in athletes treated for Achilles tendinopathy with PRP, higher quality randomized controlled trials (RCTs) have shown no clear benefit in athletes. Existing data suggest PRP significantly improves clinical outcomes for plantar fasciitis in the general population, but very few studies and no RCTs are available that specifically analyze outcomes in athletic populations. More research is needed to evaluate how platelet concentration, leukocyte and erythrocyte presence, and sport type may interact to affect clinical outcomes in athletes.

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Therapeutic efficacy of platelet-rich plasma injection compared to corticosteroid injection in plantar fasciitis: A systematic review and meta-analysis

Cited by 9 publications

References 55 publications

Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)—part VI, foot and ankle

Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)—part VI, foot and ankle

A Systematic Review of Systematic Reviews on the Epidemiology, Evaluation, and Treatment of Plantar Fasciitis

Platelet‐rich plasma injections as a treatment for Achilles tendinopathy and plantar fasciitis in athletes

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