Therapeutic effects and mechanism of action of lavender essential oil on atopic dermatitis by modulating the STAT3/RORγt pathway

The protective effects of aqueous extract of Schisandra sphenanthera against alcoholic liver disease partly through the PI3K-AKT-IKK signaling pathway

“…The collated cross-target genes were then imported into the String database ( http://string-db.org ), with the study species as “Homos Sapiens" and a confidence level of 0.7, thus obtaining the PPI network map [ 26 ]. The EnsembLID and log2fc of the intersecting genes were used for KEGG and GO enrichment analyses using R software [ 27 , 28 ].…”

Therapeutic Potential of Essential Oils Against Ulcerative Colitis: A Review

“…Transdermal administration is a common mode of essential oil delivery, which has the advantages of high bioavailability, low adverse effects and good patient compliance. 40 , 41 Li et al 42 human in the treatment of DNCB-induced atopic dermatitis with rosemary EOs, observed improved skin lesions in mice coated with rosemary essential oil, a significant reduction in serum IL-6, TNF-α, as well as in skin tissues with decreased expression of p-JAK1, CD4+ cells, IL-4, p-P65/P65, p-STAT3/STAT3 protein expression was reduced. Pires F Q et al 43 utilized HP-β-CD and nanostructured lipid carrier (NLC) for encapsulation of EOs, which solved the problem of volatility and solubility of EOs while achieving the control of the drug release rate and improved the utilization of EOs for transdermal administration.…”