Therapeutic Delivery Potential of Covalent Organic Framework (COF): Intuition from Theoretical Calculations
Mohsen D. Mohammadi,
Hitler Louis,
Innocent Benjamin
et al.
Abstract:Regardless of the benefits, pharmaceutical companies are reticent to engage further in covalent organic framework‐based drug development and drug delivery systems, preferring rather to explore preexisting chemical compound libraries for drug delivery. As such, this study aims to account for the efficacy of covalent organic frameworks (COFs) in the delivery of seven conventional drugs: Acetaminophen, Clodronic Acid, Hydroxyurea, Mercaptoporine, Thiotepa, Tioguanine, and Arsenic trioxide. Herein, Gaussian 16 sof… Show more
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