Therapeutic Contact Lenses

Smiddy, William E.; Hamburg, Tracey R.; Kracher, Gregory P.; Gottsch, John D.; Stark, Walter J.

doi:10.1016/s0161-6420(90)32589-7

Cited by 37 publications

(13 citation statements)

References 5 publications

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“…Topical corticosteroids and nonsteroidal medications appear to have no benefit in dogs . In human patients, treatment options include therapeutic soft contact lenses, anterior stromal puncture with or without neodymium: yttrium–aluminum–garnet laser, phototherapeutic keratectomy, conjunctival flaps, and amniotic membrane transplantation . In dogs, thermokeratoplasty and conjunctival flaps have been proposed for the treatment of BK.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Famose

2015

Veterinary Ophthalmology

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Section: Introductionmentioning

confidence: 99%

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Famose

2015

Veterinary Ophthalmology

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“…Ocular pain and epithelial breakdown can be treated with topical administration of steroid and hypertonic eye drops 1,2 along with the application of bandage contact lenses. 3,4 Alternative surgical interventions with variable success include anterior stromal punctures, 5 excimer laser phototherapeutic keratectomy 6 and conjunctival flap in severe cases. 7 Amniotic membrane (AM) has been shown to be effective in treating persistent corneal epithelial defects with ulceration.…”

Section: Introductionmentioning

confidence: 99%

Cryopreserved amniotic membrane transplantation for the management of symptomatic bullous keratopathy

Georgiadis¹,

Ziakas²,

Boboridis³

et al. 2008

Clinical Exper Ophthalmology

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“…Pain relief associated with corneal diseases has been reported in a recent series of 40 patients. 105 Several studies have demonstrated symptom relief with therapeutic soft CLs in patients with ocular surface disease, such as ocular graft versus host disease (GVHD). 106,107 Similarly, soft lenses improved OSDI scores as compared to AST in patients with Sjögren’s syndrome DED.…”

Section: Management Of Patients With Neuropathic Corneal Painmentioning

confidence: 99%

Neuropathic Corneal Pain

2017

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Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined disease. Patients with NCP are extremely challenging to manage and evidence-based clinical recommendations for the management of patients with NCP are scarce. The objectives of this review are to provide guidelines for diagnosis and treatment of patients with NCP and to summarize current evidence-based literature in this area. We performed a systematic literature search of all relevant publications between 1966 and 2017. Treatment recommendations are, in part, based on methodologically sound randomized controlled trials (RCTs), demonstrating superiority to placebo or relevant control treatments, and on the consistency of evidence, degree of efficacy, and safety. In addition, the recommendations include our own extensive experience in the management of these patients over the past decade. A comprehensive algorithm, based on clinical evaluation and complementary tests, is presented for diagnosis and subcategorization of patients with NCP. Recommended first-line topical treatments include neuro-regenerative and anti-inflammatory agents, whilst first-line systemic pharmacotherapy includes tricyclic antidepressants and the anticonvulsant. Second line oral treatments recommended include the opioid-antagonist and opiate analgesics. Complementary and alternative treatments, such as cardio-exercise, acupuncture, omega-3 fatty acid, and gluten-free diet, may have additional benefits, as do potential non-invasive and invasive procedures in recalcitrant cases. Medication selection should be tailored on an individual basis, considering side effects, comorbidities, and levels of peripheral and centralized pain. Nevertheless, there is an urgent need for long-term studies and RCTs assessing the efficacy of treatments for NCP.

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Therapeutic Contact Lenses

Cited by 37 publications

References 5 publications

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Cryopreserved amniotic membrane transplantation for the management of symptomatic bullous keratopathy

Neuropathic Corneal Pain

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