Therapeutic Claims in Cannabidiol (CBD) Marketing Messages on Twitter

Soleymanpour, Mohammad; Saderholm, Sofia; Kavuluru, Ramakanth

doi:10.1109/bibm52615.2021.9669404

Cited by 24 publications

(27 citation statements)

References 14 publications

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“…Cannabidiol (CBD), a non-psychotropic component of Cannabis sativa L., is regularly consumed by millions of people, in part because of the belief that it bestows a variety of health benefits [ 1 ]. Based on recent reviews, it appears that CBD may indeed bestow some health benefits, but in general the claims likely outweigh the supporting evidence [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function

et al. 2022

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Cannabidiol (CBD) is widely available and marketed as having therapeutic properties. Over-the-counter CBD is unregulated, many of the therapeutic claims lack scientific support, and controversy exists as to the safety of CBD-liver interaction. The study aims were to compare the pharmacokinetics of commercial CBD and CBD metabolites following the ingestion of five different CBD formulations, determine the influence of CBD on food induced thermogenesis, determine the influence of food on CBD pharmacokinetics, and determine the influence of CBD on markers of liver function. Fourteen males (body mass index ³ 25 kg/m2) were studied in a placebo-controlled, randomized, crossover design. On five occasions, different CBD formulations were ingested (one per visit). On two additional occasions, CBD or placebo was ingested following a meal. CBD servings were standardized to 30 mg. Considerable pharmacokinetic variability existed between formulations; this pharmacokinetic variability transferred to several of the metabolites. CBD did not influence food induced thermogenesis but did favorably modify early insulin and triglyceride responses. Food appreciably altered the pharmacokinetics of CBD. Finally, CBD did not evoke physiologically relevant changes in markers of liver function. Collectively, these data suggest that consumers should be aware of the appreciable pharmacokinetic differences between commercial CBD formulations, CBD is unlikely to influence the caloric cost of eating but may prove to be of some benefit to initial metabolic responses, consuming CBD with food alters the dynamics of CBD metabolism and increases systemic availability, and low-dose CBD probably does not represent a risk to normal liver function.

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Section: Introductionmentioning

confidence: 99%

Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function

et al. 2022

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“…Studies that utilized a large volume of data allowed for the use of computational methods, including sentiment analysis, topic modeling, and rule-based text mining. Sentiment analysis aims to analyse people's sentiments, opinions, and attitudes (75,77). Topic modelling is a machine learning method for automatically discovering common themes in a collection of documents (75,78).…”

Section: Discussionmentioning

confidence: 99%

“…Sentiment analysis aims to analyse people's sentiments, opinions, and attitudes (75,77). Topic modelling is a machine learning method for automatically discovering common themes in a collection of documents (75,78). Rule-based text mining involves classification of posts into pre-existing health-related categories (76).…”

Section: Discussionmentioning

confidence: 99%

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Social media discourse and internet search queries on cannabis as a medicine: A systematic scoping review

Habibabadi

Bonomo

Conway

et al. 2022

Preprint

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ObjectiveTo systematically review the current published literature that uses social media data and internet search engine queries to identify emerging themes on the use of cannabis as a medicine. In this study, the term cannabis as a medicine refers to the use of cannabis with therapeutic intent and includes prescribed cannabis, over-the-counter cannabis, and non-prescribed cannabis used specifically for self-medication (not for recreational purposes).Materials and MethodsFor this systematic review, Medline, Scopus, Web of Science and Embase databases were searched for peer reviewed studies published in English between January 2010 and March 2022. All study types that examined social media data and cannabis as a medicine were included in the review.ResultsForty studies were included in this review. 21 studies used manually labeled data, 4 studies used existing meta-data, 2 studies used data from social media analytics companies and 13 used computational methods for annotating data. More than half of the studies 22/40 (55%), were published in the last three years. The incidental use of cannabis as a medicine was found in eleven studies that were focused on more general health-related issues, rather than on medicinal cannabis only.ConclusionOur systematic review has revealed the growing interest in analyzing user-generated content for studying cannabis as a medicine. This review has also highlighted the need for studies into cannabis use for specific health conditions and for automatic processing of larger datasets using computational methods (machine learning technologies).

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“…CBD has been promoted more widely, certainly among social media, 43 as a cannabinoid with sedating properties. However, there is limited robust evidence for this notion.…”

Section: Effect Of Cbd On Insomniamentioning

confidence: 99%

Is There a Place for Medicinal Cannabis in Treating Patients with Sleep Disorders? What We Know so Far

Maddison¹,

Kosky²,

Walsh³

2022

NSS

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The legalization of cannabis for medicinal, and in some countries, recreational, purposes in addition to growth in the cannabis industry has meant that cannabis use and interest in the area has increased rapidly over the past 20 years. Treatment of poor sleep and sleep disorders are two of the most common reasons for the current use of medicinal cannabis. However, evidence for the role of medical cannabis in the treatment of sleep disorders has not been clearly established, thus making it challenging for clinicians to make evidence-based decisions regarding efficacy and safety. This narrative review summarizes the highest quality clinical evidence currently available in relation to the use of medicinal cannabis for the treatment of sleep disorders including insomnia, obstructive sleep apnea, restless legs syndrome, rapid eye movement sleep behavior disorder, nightmare disorder and narcolepsy. A summary of the effect of cannabis on sleep quality and architecture is also presented. Currently, there is insufficient evidence to support the routine use of medicinal cannabis as an effective and safe treatment option for any sleep disorder. Nevertheless, emerging evidence is promising and warrants further investigation using standardized cannabinoid products and validated quantitative measurement techniques.

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Therapeutic Claims in Cannabidiol (CBD) Marketing Messages on Twitter

Cited by 24 publications

References 14 publications

Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function

Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function

Social media discourse and internet search queries on cannabis as a medicine: A systematic scoping review

Is There a Place for Medicinal Cannabis in Treating Patients with Sleep Disorders? What We Know so Far

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