Therapeutic Avenues to Modulate B-Cell Function in Patients With Cardiovascular Disease
James W. O’Brien,
Ayden Case,
Claudia Kemper
et al.
Abstract:The adaptive immune system plays an important role in the development and progression of atherosclerotic cardiovascular disease. B cells can have both proatherogenic and atheroprotective roles, making treatments aimed at modulating B cells important therapeutic targets. The innate-like B-cell response is generally considered atheroprotective, while the adaptive response is associated with mixed consequences for atherosclerosis. Additionally, interactions of B cells with components of the adaptive and innate im… Show more
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