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2015
DOI: 10.21767/2471-8505.10006
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Therapeutic Approaches to Combatting Hypermetabolism in Severe Burn Injuries

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Cited by 11 publications
(13 citation statements)
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References 146 publications
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“…During the acute phase it is important to also evaluate the color of the urine (dark urine is a sign of myoglobinuria that may appear in massive burns or electrical burns)-if the color is dark, it is a high suspicion of kidney failure, requiring aggressive and prompt treatment 1 . Th is fi rst phase, described as the ebb phase lasts the 48-72 hours of thermal injury with patients presenting oxygen consumption, decreased cardiac output and metabolic rate and are both glucose intolerant and hyperglycemic 42 . Th e primary goal after the acute phase is to restore and preserve tissue perfusion and prevent ischemia produced by post-combustion shock with hypovolemic and cellular disorders 43 .…”
Section: Discussionmentioning
confidence: 99%
“…During the acute phase it is important to also evaluate the color of the urine (dark urine is a sign of myoglobinuria that may appear in massive burns or electrical burns)-if the color is dark, it is a high suspicion of kidney failure, requiring aggressive and prompt treatment 1 . Th is fi rst phase, described as the ebb phase lasts the 48-72 hours of thermal injury with patients presenting oxygen consumption, decreased cardiac output and metabolic rate and are both glucose intolerant and hyperglycemic 42 . Th e primary goal after the acute phase is to restore and preserve tissue perfusion and prevent ischemia produced by post-combustion shock with hypovolemic and cellular disorders 43 .…”
Section: Discussionmentioning
confidence: 99%
“…Proper nutrition is crucial to supply the required energy for wound recovery and attenuation of the hypermetabolism and protein catabolism that occur in individuals who suffered severe burns 29 . The data were positive given that no child was classified as undernourished and most were eutrophic, but one should clinically consider those classified as overweight or obese, since childhood obesity is regarded as a public health problem not only in Brazil, but around the world 13,30,31 .…”
Section: Discussionmentioning
confidence: 99%
“…Uždegimas, hipermetabolizmas, raumenų jėgos, atsparumo insulinui sumažėjimas, patofiziologiniai pokyčiai galimi dėl sunkios nudegimų traumos. Dėl nudegimų traumos išsivystęs baltymų katabolizmas, liesosios kūno masės netekimas ir jį lydintis raumenų jėgos sumažėjimas, gali tęstis ir po žaizdų užgijimo praėjus 9-12 mėnesių ar net keletą metų (Bakhtyar et al, 2015;Saeman et al, 2015;Nielson et al, 2017). C. Porterʼis su bendraautoriais (2015) atliko tyrimą su didelės apimties nudegimų traumą patyrusiais suaugusiais ligoniais ir pastebėjo sutrikusią mitochondrijų funkciją, didėjančią mitochondrijų termogenezę.…”
Section: Raumenų Jėgos Pokyčiai Po Nudegimų Traumos Ir Kineziterapijaunclassified
“…Deguonies suvartojimas po nudegimų traumos viršija ATF produkciją. Jėgos pratimų atlikimas akivaizdžiai pagerina mitochondrijų funkciją ir ATF gamybą (Bakhtyar et al, 2015). Sveikiems, bet gulintiems tiriamiesiems nuo pirmos nejudėjimo dienos jėgos pratimų taikymas apsaugo juos nuo baltymų sintezės raumenyse sumažėjimo (Pavoni et al, 2010).…”
Section: Raumenų Jėgos Pokyčiai Po Nudegimų Traumos Ir Kineziterapijaunclassified