Therapeutic Applications of Biogenic Silver Nanomaterial Synthesized from the Paper Flower of Bougainvillea glabra (Miami, Pink)

Abstract

In this research, Bougainvillea glabra paper flower extract was used to quickly synthesize biogenic silver nanoparticles (BAgNPs) utilizing green chemistry. Using the flower extract as a biological reducing agent, silver nanoparticles were generated by the conversion of Ag+ cations to Ag0 ions. Data patterns obtained from physical techniques for characterizing BAgNPs, employing UV-visible, scattering electron microscope (SEM), transmission electron microscope (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR), suggested that the nanoparticles have a spherical to oval form with size ranging from 10 to 50 nm. Spectroscopy and microscopic analysis were used to learn more about the antibacterial properties of the biologically produced BAgNPs from Bougainvillea glabra. Further, the potential mechanism of action of nanoparticles was investigated by studying their interactions in vitro with several bacterial strains and mammalian cancer cell systems. Finally, we can conclude that BAgNPs can be functionalized to dramatically inhibit bacterial growth and the growth of cancer cells in culture conditions, suggesting that biologically produced nanomaterials will provide new opportunities for a wide range of biomedical applications in the near future.

Biofabrication of nanoparticles: sources, synthesis, and biomedical applications

“…The particular spectrum displayed peaks from XRD. The XRD peak patterns and different diffraction peak values, which show the reflection planes, demonstrate the nature of the produced materials ( Oves et al, 2023 ).…”

Comprehensive antifungal investigation of green synthesized silver nanoformulation against four agriculturally significant fungi and its cytotoxic applications

“…The toxic chemicals, capping agents, and reducing agents in these methods have detrimental effects on the environment. Therefore, there is a vital need for an alternative, eco-sustainable approach 41 . Earlier reported literature highlighted green synthesis as a non-toxic, environmentally friendly, cost-effective, and sustainable approach 42 , 43 .…”

“…The plant leaf extract contains secondary compounds that serve as precursor molecules, acting as reducing, capping, and stabilizing agents for nanoparticle synthesis 48 . The nanoparticles synthesized through the green method employing aqueous plant leaf extract are more effective and possess superior antimicrobial properties than those that are produced via thermal, chemical, or other biological routes 41 .…”

Green synthesis of silver nanoparticles by using Allium sativum extract and evaluation of their electrical activities in bio-electrochemical cell

“…Ag NPs reveal an important role in the development of devices and biological applications by showing excellent physicochemical properties [12,13]. The unique activities of Ag NPs as a catalyst, antibacterial, antifungal, anticancer, and therapeutic agents have been reported vastly in recent decades [14][15][16][17].…”

“…Three key principles of green chemistry should be taken into account while synthesizing nanoparticles: selecting (i) an eco-friendly solvent for the synthesis; (ii) a benign reducing agent; and (iii) a non-toxic substance to acts as a stabilizer [7]. It has been observed that plant components such as the bark, fruit, root, bulb, flower, pulp, peel, callus, seed, stem, and leaves are excellent sources for the synthesis of NPs [16,17,22,23]. The size, shape, and properties of nanoparticles are varied according to the variety of plant extract-reducing agents and their optimum concentration [2,3,24].…”